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Miles Davenport
School of Medical Sciences, University of New South Wales
A quantitative approach to vaccine development for HIV
Wednesday 10th August 14:05-14:55pm,
Carslaw Building Room 373.
A number of vaccines for HIV are currently being developed and tested
in monkeys. In collaboration with experimentalists carrying out this
work, we have applied statistical analysis and ODE modelling to
understand the kinetics of the immune response, as well as the impact
of immune response on infection. In addition, we have developed
epidemiological models to predict the impact of vaccination on the
outcome of the epidemic. This analysis reveals significant limitations
in the ability of vaccines to control virus. However, epidemiological
modelling suggests that even partially effective vaccines may help
control the epidemic.
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