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David Terman
Mathematical Biosciences Institute & Department of Mathematics, The Ohio State University
A mathematical model for Parkinsonian rhythms
Wednesday 29th August 14:05-14:55pm,
Eastern Avenue Lecture Theatre.
I will describe a model for neuronal activity patterns within the basal ganglia, a group of neurons deep inside the brain that is involved in the generation of movements. Dysfunction of the basal ganglia leads to movement disorders such as Parkinson's disease. Experiments have demonstrated that there is a change in firing patterns between normal and pathological conditions and we present a model that is able to generate these types of firing patterns. I will also describe a model for mechanisms underlying the beneficial affects of deep brain stimulation, a therapeutic procedure used in the treatment of Parkinson's disease.
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