Professor Gemma Figtree
Medicine, Northern Clinical School
Kolling Institute of Medical Research
Gemma Figtree is a Professor in Medicine at the University of Sydney. She co-leads the Cardiovascular Theme for Sydney Health Partners, a NHMRC Advanced Health Research and Translation Centre and is the Chair of the University of Sydney’s multi-disciplinary Cardiovascular Initiative.
Gemma completed her DPhil at Oxford University in 2002 supported by a Rhodes Scholarship making fundamental discoveries regarding estrogen’s actions and factors regulating NO/redox balance in the cardiovascular system. She is committed to improving the care for heart attack patients- using her knowledge of molecular and cellular biology to develop methods of identifying those at highest risk of adverse outcome, and discovering novel therapies to prevent and treat events,inspired by her clinical work as an interventional cardiologist.She has dedicated herself throughout her career to unravelling key mechanisms underlying susceptibility and response to heart attack, with studies extending from the bench to large cohort studies and clinical trials.
Discoveries in Prof Figtree's Laboratory have been published in leading journals Circulation, JACC and European Heart Journal, with > 150 publications. She is a principal investigator on grants >$8 mill. Having recently completed a co-funded NHMRC CDF and Heart Foundation Future Leader Fellowship, she was awarded a NHMRC Excellence Award for Top Ranked Practitioner Fellow (Australia), commencing in 2018. In 2019 she received the prestigious NSW Ministerial Award for Cardiovascular Research Excellence.
Prof Figtree is committed to the advancement of her field and serves as a member of the Editorial Board of leading international cardiovascular journals, includingCirculation,andCardiovascular Research, as well as being a founding editorial board member forRedox Biology, and an Associate Editor forHeart, Lung and Circulation.
Professor Figtree is committed to the promotion and advocacy of cardiovascular research, working as President of the Australian Cardiovascular Alliance with a national team to secure $220 Million Federal funding for the Mission for Cardiovascular Health, as well as being a member of the NSW CVD Advisory Committee. She has been appointed by the Minister as the Chair of the MRFF Mission's (CV) Expert Advisory Panel.Her perspective and leadership are recognised by her membership of the Scientific Board of Cardiac Society of Australia and New Zealand (responsible for International Relations), and her appointment to the Expert Advisory Panel for NHMRC Structural Review of Grants Program (2016-17), and as well as the Clinical Committee of the Heart Foundation. She is a graduate of the Australian Institute of Company Directors and serves/has served as a non-executive Director on multiple community Boards.She is deeply engaged in mentorship of early and mid-career researchers from a diverse range of research and personal backgrounds.
The breadth of Dr Figtree's research program spans from discovery of fundamental mechanisms and drug targets to precision medicine, clinical trials and implementation. The syndergy that this program of work has with her clinical job as an interventional cardiologist enables her to lead unique approaches to tackling cardiovascular disease. She is passionate about bringing together the future leaders of cardiovascular research from a diverse range of backgrounds to tackle the clinical problem.
Specific clinical questions that are the focus of the Figtree team's work include:
1. Mechanisms of coronary atherosclerosis in patients with no standard modifiable risk factors;
2. New blood biomarkers to detect early atherosclerosis and predict risk of heart attack;
3. Novel drug targets that tackle inflammation and oxidative stress in the heart and blood vessel;
4. Integrating advanced cardiovascular imaging, molecular markers and clinical data to predict risk;
5. Clinical trials
Clinical and interventional cardiology
Advanced cardiovascular imaging
Molecular and redox biology
Translational strategies
We have PhD and Master's opportunities for energetic and creative research students:
1. Mechanisms of coronary atherosclerosis in patients with no standard modifiable risk factors;
2. New blood biomarkers to detect early atherosclerosis and predict risk of heart attack;
3. Novel drug targets that tackle inflammation and oxidative stress in the heart and blood vessel;
4. Integrating advanced cardiovascular imaging, molecular markers and clinical data to predict risk;
5. Clinical trials: testing new therapies, and digital applications in coronary artery disease and peripheral arterial disease.
Australian Cardiovascular Alliance
Cardiac Society of Australia and New Zealand
University of Sydney Cardiovascular Initiative
American Heart Association
Royal Australian College of Physicians
Australian Institute of Company Directors
University of Sydney Faculty of Medicine and Health Award for Excellence- Outstanding Research Leadership- 2019
NSW Ministerial Award for Cardiovascular Research Excellence, 2019
NHMRC Excellence Award for Top Ranked Practitioner Fellow, 2018.
NHMRC Practitioner Fellowship, 2018-23
NSW Women of the Year Awards: Local Woman of the Year, Northern Sydney, 2017.
Barbara Ell Invited Guest Lecture, Victor Chang Institute of Cardiovascular Research, October, 2017.
Ray Knight Award for Research Mentorship, Cardiothoracic and Vascular Health, Kolling Institute and Northern Sydney Local Health District, 2017.
Colin Johnston Invited Guest Lecturer. High Blood Pressure Research Council of Australia, 2015.
NHMRC Career Development Fellowship (Level 2), 2014-18.
National Heart Foundation, Future Leader Fellowship, 2014-18 (co-funded with NHMRC CDF as above)
Sylvia and Charles Viertel Charitable Foundation- Clinical Investigatorship, 2010-11
Chapman Fellowship, Sydney Medical School Foundation, 2009-13
Rhodes Scholarship 1999-2002
(Cardiac Medicine, National Heart and Lung Institute, Imperial College, London) Longstanding collaboration with Professor Peter Collins, with a focus on estrogen and related sex-steroids actions on the vasculature. | |
(Cardiovascular Medicine, University of Oxford.) Investigating factors involved in mediating individual susceptibility to complex cardiovascular disease- Professors Hugh Watkins and Keith Channon | |
(Harvard Medical School and Massachussets General Hospital, Boston) Collaboration with Professor Kathy Sweadner, and Dr Elena Arystarkhova, investigating the role of FXYD proteins in cardiovascular disease. |
Project title | Research student |
---|---|
Exploring evidence based management for ST segment elevation myocardial infarction patients without traditional cardiovascular risk factors | Suzanne AVIS |
The identification of a novel blood based biosignature to detect early coronary artery disease | Pich CHHAY |
Topical therapeutics in peripheral vascular disease. | Cameron EVANS |
Utilising Patient Endothelial Colony Forming Cells as a Model for Investigating Redox signatures and Drug Targets for Coronary Artery Disease | Eugene LEE |
State-of-the-art cardiac diagnostic techniques to improve diagnosis and management of heart disease | Manoj RAJAMOHAN |
Coronary microvascular dysfunction and risk factors | Sascha Swaraj SWARAJ |
Selected publications
Publications
Books
- Figtree, G. (2009). Genetic Variants in Estrogen Signaling Pathways. Germany: VDM Verlag.
Book Chapters
- Vernon, S., O'Sullivan, J., Figtree, G. (2019). Metabolic signatures of redox-dependent cardiovascular diseases. In Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit (Eds.), Oxidative Stress in Heart Diseases., (pp. 159-171). Singapore: Springer Nature Singapore. [More Information]
Journals
- La Gerche, A., Dennis, M., Figtree, G., Kovacic, J., Maris, J., Nehme, Z., Parsons, S., Pflaumer, A., Puranik, R., Stub, D., et al (2024). A Call to Action to Improve Cardiac Arrest Outcomes: A Report From the National Summit for Cardiac Arrest. Heart, Lung, and Circulation. [More Information]
- Kumar, A., Huangfu, G., Figtree, G., Dwivedi, G. (2024). Atherosclerosis as the Damocles' sword of human evolution: insights from nonhuman ape-like primates, ancient human remains, and isolated modern human populations. American Journal of Physiology - Heart and Circulatory Physiology, 326(3), H821-H831. [More Information]
- Nurmohamed, N., Rodriguez, F., Sandhu, A., Nieman, K., Earls, J., Bax, J., Maron, D., Bhatt, D., van Rosendael, A., Danad, I., Figtree, G., et al (2024). Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography. European Heart Journal, 45(20), 1783-1800. [More Information]
- Lan, N., Chih, H., Brennan, A., Dwivedi, G., Figtree, G., Dinh, D., Stub, D., Reid, C., Ihdayhid, A. (2024). Clinical outcomes and coronary artery lesion characteristics of young patients with ST elevation myocardial infarction and no standard modifiable risk factors. Catheterization and Cardiovascular Interventions. [More Information]
- Howden, N., Branch, K., Douglas, P., Gray, M., Budoff, M., Dewey, M., Newby, D., Nicholls, S., Blankstein, R., Fathieh, S., Grieve, S., Figtree, G. (2024). Computed tomographic angiography measures of coronary plaque in clinical trials: opportunities and considerations to accelerate drug translation. Frontiers in Cardovascular Medicine, 11. [More Information]
- Tran, A., Wang, A., Mickaill, J., Strbenac, D., Larance, M., Vernon, S., Grieve, S., Figtree, G., Patrick, E., Yang, J. (2024). Construction and optimization of multi-platform precision pathways for precision medicine. Scientific Reports, 14(Article 4248), 1-11.
- Deshmukh, T., Selvakumar, D., Thavapalachandran, S., Archer, O., Figtree, G., Feneley, M., Grieve, S., Thomas, L., Pathan, F., Chong, J. (2024). Correlation of Noninvasive Cardiac MRI Measures of Left Ventricular Myocardial Function and Invasive PressureVolume Parameters in a Porcine Ischemia-Reperfusion Model. Radiology: Cardiothoracic Imaging, 6(3). [More Information]
- Candelaria, D., Redfern, J., O'Neil, A., Brieger, D., Clark, R., Briffa, T., Bauman, A., Hyun, K., Cunich, M., Figtree, G., Gallagher, R., et al (2024). Data-driven collaborative QUality improvement in Cardiac Rehabilitation (QUICR) to increase program completion: protocol for a cluster randomized controlled trial. BMC Cardiovascular Disorders, 24(1). [More Information]
- Hernandez, A., Amir, O., Bahit, M., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., et al (2024). Effect of Empagliflozin on Heart Failure Outcomes after Acute Myocardial Infarction: Insights from the EMPACT-MI Trial. Circulation, 149(21), 1627-1638. [More Information]
- BUTLER, J., Bahit, M., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., et al (2024). Empagliflozin after Acute Myocardial Infarction. New England Journal of Medicine, 390(16), 1455-1466. [More Information]
- Gray, M., Fatkin, D., Ingles, J., Robertson, E., Figtree, G. (2024). Genetic testing in cardiovascular disease. Medical Journal of Australia, 220(8), 428-434. [More Information]
- Lee, E., Besnier, M., Genetzakis, E., Tang, O., Kott, K., Vernon, S., Gray, M., Grieve, S., Kassiou, M., Figtree, G. (2024). High-Throughput Measure of Mitochondrial Superoxide Levels as a Marker of Coronary Artery Disease to Accelerate Drug Translation in Patient-Derived Endothelial Cells Using Opera Phenix® Technology. International Journal of Molecular Sciences, 25(1). [More Information]
- Desson, Z., Figtree, G., Webster, J., Jennings, G., Redfern, J., Nicholls, S., McNamara, M., Deeming, S., Doyle, K., Ramanathan, S., Morton, R., et al (2024). Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, 38(2), 177-186. [More Information]
- Dakic, A., Wu, J., Wang, T., Huynh, K., Mellett, N., Duong, T., Beyene, H., Yang, J., Figtree, G., Simes, R., et al (2024). Imputation of plasma lipid species to facilitate integration of lipidomic datasets. Nature Communications, 15(1), 1540. [More Information]
- Udell, J., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., Goto, S., et al (2024). Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction. Journal of the American College of Cardiology, 83(23), 2233-2246. [More Information]
- Wu, J., Giles, C., Dakic, A., Beyene, H., Huynh, K., Wang, T., Meikle, T., Olshansky, G., Salim, A., Duong, T., Zhu, D., Yang, J., Grieve, S., Wilson, A., Chow, C., Vernon, S., Gray, M., Figtree, G., et al (2024). Lipidomic Risk Score to Enhance Cardiovascular Risk Stratification for Primary Prevention. Journal of the American College of Cardiology, 84(5), 434-446.
- Lu, J., Bisson, A., Bennamoun, M., Zheng, Y., Sanfilippo, F., Hung, J., Briffa, T., McQuillan, B., Stewart, J., Figtree, G., et al (2024). Predicting multifaceted risks using machine learning in atrial fibrillation: insights from GLORIA-AF study. European Heart Journal - Digital Health, 5(3), 235-246. [More Information]
- Gray, M., Vogel, B., Mehran, R., Leopold, J., Figtree, G. (2024). Primary prevention of cardiovascular disease in women. Climacteric, 27(1), 104-112. [More Information]
- Buckler, A., Kolossváry, M., Konrad, M., Lal, B., Marques, H., Moss, A., Obuchowski, N., van Beek, E., Virmani, R., Williams, M., Figtree, G., et al (2024). Special Report on the Consensus QIBA Profile for Objective Analytical Validation of Non-calcified and High-risk Plaque and Other Biomarkers using Computed Tomography Angiography. Academic Radiology. [More Information]
- Figtree, G., Doyle, K., Nedkoff, L., Cadilhac, D., Kovacic, J. (2024). The national Cardiovascular Health Leadership Research Forum: a new data-driven model placing research at the centre of improving patient outcomes. Medical Journal of Australia. [More Information]
- Kong, G., Mehta, A., Figtree, G., Mamas, M., Ng, G., Chan, K., Chai, P., Low, A., Lee, C., Yeo, T., et al (2024). The prognostic value of metabolic dysfunction-associated steatotic liver disease in acute myocardial infarction: A propensity score-matched analysis. Diabetes, Obesity and Metabolism, 26(8), 3328-3338. [More Information]
- Bate, K., Genetzakis, E., Vescovi, J., Gray, M., Celermajer, D., McGuire, H., Grieve, S., Vernon, S., Cartland, S., Yang, J., Kavurma, M., Figtree, G. (2024). Vascular Cytokines and Atherosclerosis: Differential Serum Levels of TRAIL, IL-18, and OPG in Obstructive Coronary Artery Disease. Biomolecules, 14, 1119. [More Information]
- Karimi Galougahi, K., Zhang, Y., Kienzle, V., Liu, C., Quek, L., Patel, S., Lau, E., Cordina, R., Figtree, G., Celermajer, D. (2023). β3 adrenergic agonism: A novel pathway which improves right ventricular-pulmonary arterial hemodynamics in pulmonary arterial hypertension. Physiological Reports, 11(1). [More Information]
- Kavurma, M., Aitken, S., Boccanfuso, L., Cutmore, C., Passam, F., Patel, S., Hennessy, A., Loa, J., Figtree, G., Golledge, J. (2023). A hidden problem: peripheral artery disease in women. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 342-350. [More Information]
- Kong, G., Chin, Y., Lim, J., Ng, C., Kannan, S., Chong, B., Lin, C., Chan, K., Anand, V., Lee, E., Figtree, G., et al (2023). A two-decade population-based study on the effect of hypertension in the general population with obesity in the United States. Obesity, 31(3), 832-840. [More Information]
- Kelly, C., Lan, N., Phan, J., Hng, C., Matthews, A., Rankin, J., Schultz, C., Hillis, G., Reid, C., Dwivedi, G., Figtree, G., et al (2023). Characteristics and Outcomes of Young Patients With ST-Elevation Myocardial Infarction Without Standard Modifiable Risk Factors. American Journal of Cardiology, 202, 81-89. [More Information]
- Figtree, G., Vernon, S., Harmer, J., Gray, M., Arnott, C., Bachour, E., Barsha, G., Brieger, D., Brieger, D., O'Sullivan, J. (2023). Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 82(13), 1343-1359. [More Information]
- Kong, G., Chin, Y., Chong, B., Goh, R., Lim, O., Ng, C., Muthiah, M., Foo, R., Vernon, S., Loh, P., Figtree, G., et al (2023). Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: Results from a global meta-analysis of 1,285,722 patients. International Journal of Cardiology, 371, 432-440. [More Information]
- Deshmukh, T., Kovoor, J., Byth, K., Chow, C., Zaman, S., Chong, J., Figtree, G., Thiagalingam, A., Kovoor, P. (2023). Influence of standard modifiable risk factors on ventricular tachycardia after myocardial infarction. Frontiers in Cardovascular Medicine, 10. [More Information]
- Sokhal, B., Matetic, A., Paul, T., Velagapudi, P., Lambrinou, E., Figtree, G., Rashid, M., Moledina, S., Vassiliou, V., Mallen, C., et al (2023). Management and outcomes of patients admitted with type 2 myocardial infarction with and without standard modifiable risk factors. International Journal of Cardiology, 371, 391-396. [More Information]
- Kott, K., Chan, A., Vernon, S., Hansen, T., Kim, T., De Dreu, M., Gunasegaran, B., Murphy, A., Patrick, E., Psaltis, P., Grieve, S., Yang, J., Fazekas de St Groth, B., McGuire, H., Figtree, G. (2023). Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease. Clinical & Translational Immunology, 12(11), e1462-1-e1462-18. [More Information]
- Chin, Y., Lim, O., Lin, C., Chan, Y., Kong, G., Ng, C., Chong, B., Syn, N., Chan, K., Muthiah, M., Figtree, G., et al (2023). Meta-Analysis of the Placebo and Nocebo effects associated with Placebo treatment in randomized trials of lipid-lowering therapies. European Heart Journal - Quality of Care and Clinical Outcomes, 9(5), 511-519. [More Information]
- Lee, E., Genetzakis, E., Figtree, G. (2023). Novel Strategies in the Early Detection and Treatment of Endothelial Cell-Specific Mitochondrial Dysfunction in Coronary Artery Disease. Antioxidants, 12(7). [More Information]
- Chan, A., Wu, S., Vernon, S., Tang, O., Figtree, G., Liu, T., Yang, J., Patrick, E. (2023). Overcoming cohort heterogeneity for the prediction of subclinical cardiovascular disease risk. iScience, 26(5), Article 106633 - 1-Article 106633 - 17. [More Information]
- Fathieh, S., Grieve, S., Negishi, K., Figtree, G. (2023). Potential Biological Mediators of Myocardial and Vascular Complications of Air Pollution—A State-of-the-Art Review. Heart, Lung, and Circulation, 32(1), 26-42. [More Information]
- Cho, K., French, J., Figtree, G., Chow, C., Kozor, R. (2023). Rapid access chest pain clinics in Australia and New Zealand. Medical Journal of Australia, 219(4), 168-172. [More Information]
- Kott, K., Genetzakis, E., Gray, M., Hansen, P., McGuire, H., Yang, J., Grieve, S., Vernon, S., Figtree, G. (2023). Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease. Biomolecules, 13(8), 1187-17 pages. [More Information]
- Burgess, S., Shoaib, A., Sharp, A., Ludman, P., Graham, M., Figtree, G., Kontopantelis, E., Rashid, M., Kinnaird, T., Mamas, M. (2023). Sex-Specific Differences in Potent P2Y12Inhibitor Use in British Cardiovascular Intervention Society Registry STEMI Patients. Circulation: Cardiovascular Interventions, 16(9), E012447. [More Information]
- Anand, V., Zhe, E., Chin, Y., Goh, R., Lin, C., Kueh, M., Chong, B., Kong, G., Tay, P., Dalakoti, M., Figtree, G., et al (2023). Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices. International Journal of Cardiology, 383, 140-150. [More Information]
- Gallagher, R., Chow, C., Parker, H., Neubeck, L., Celermajer, D., Redfern, J., Tofler, G., Buckley, T., Schumacher, T., Hyun, K., Boroumand, F., Figtree, G. (2023). The effect of a game-based mobile app 'MyHeartMate' to promote lifestyle change in coronary disease patients: a randomized controlled trial. European Heart Journal - Digital Health, 4(1), 33-42. [More Information]
- Chew, N., Ng, C., Tan, D., Kong, G., Lin, C., Chin, Y., Lim, W., Huang, D., Quek, J., Fu, C., Figtree, G., et al (2023). The global burden of metabolic disease: Data from 2000 to 2019. Cell Metabolism, 35(3), 414-428.e3. [More Information]
- Chong, B., Kong, G., Kannan, S., Chew, H., Lin, C., Goh, R., Chin, Y., Tan, D., Chan, K., Lim, W., Figtree, G., et al (2023). The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019. Metabolism: Clinical and Experimental, 141. [More Information]
- Leslie, F., Avis, S., Bagnall, R., Bendall, J., Briffa, T., Brouwer, I., Butters, A., Figtree, G., La Gerche, A., Gray, B., Semsarian, C., Sy, R., Yeates, L., et al (2023). The New South Wales Sudden Cardiac Arrest Registry: A Data Linkage Cohort Study. Heart, Lung, and Circulation, 32(9), 1069-1075. [More Information]
- Nour, D., Allahwala, U., Hansen, P., Figtree, G., Nelson, G., Ward, M., Bhindi, R. (2022). Angiographic predictors of coronary hemodynamics. Future Cardiology, 18(4), 299-308. [More Information]
- Sharma, P., Liu Chung Ming, C., Wang, X., Bienvenu, L., Beck, D., Figtree, G., Boyle, A., Gentile, C. (2022). Biofabrication of advancedin vitro3D models to study ischaemic and doxorubicin-induced myocardial damage. Biofabrication, 14(2), 25003. [More Information]
- Kott, K., Bishop, M., Yang, C., Plasto, T., Cheng, D., Kaplan, A., Cullen, L., Celermajer, D., Meikle, P., Vernon, S., Figtree, G. (2022). Biomarker Development in Cardiology: Reviewing the Past to Inform the Future. Cells, 11(3), 588. [More Information]
- Barraclough, J., Yu, J., Figtree, G., Perkovic, V., Heerspink, H., Neuen, B., Cannon, C., Mahaffey, K., Schutte, A., Neal, B., Arnott, C. (2022). Cardiovascular and renal outcomes with canagliflozin in patients with peripheral arterial disease: Data from the CANVAS Program and CREDENCE trial. Diabetes, Obesity and Metabolism, 24(6), 1072-1083. [More Information]
- Sarraju, A., Bakris, G., Cannon, C., Cherney, D., Damaraju, C., Figtree, G., Gogate, J., Greene, T., Heerspink, H., Januzzi, J., Jardine, M., et al (2022). Cardiovascular Effects of Canagliflozin in Relation to Renal Function and Albuminuria. Journal of the American College of Cardiology, 80(18), 1721-1731. [More Information]
- Mazhar, J., Ekström, K., Kozor, R., Grieve, S., Nepper-Christensen, L., Ahtarovski, K., Kelbæk, H., Høfsten, D., Køber, L., Vejlstrup, N., Vernon, S., Figtree, G., et al (2022). Cardiovascular magnetic resonance characteristics and clinical outcomes of patients with ST-elevation myocardial infarction and no standard modifiable risk factors–A DANAMI-3 substudy. Frontiers in Cardovascular Medicine, 9. [More Information]
- Figtree, G., Redfors, B., Kozor, R., Vernon, S., Grieve, S., Mazhar, J., Thiele, H., Patel, M., Udelson, J., Selker, H., et al (2022). Clinical Outcomes in Patients With ST-Segment Elevation MI and No Standard Modifiable Cardiovascular Risk Factors. JACC: Cardiovascular Interventions, 15(11), 1167-1175. [More Information]
- Sia, C., Ko, J., Zheng, H., Ho, A., Foo, D., Foo, L., Lim, P., Liew, B., Chai, P., Yeo, T., Figtree, G., et al (2022). Comparison of Mortality Outcomes in Acute Myocardial Infarction Patients With or Without Standard Modifiable Cardiovascular Risk Factors. Frontiers in Cardovascular Medicine, 9. [More Information]
- McKinn, S., Batcup, C., Cornell, S., Freeman, N., Doust, J., Bell, K., Figtree, G., Bonner, C. (2022). Decision Support Tools for Coronary Artery Calcium Scoring in the Primary Prevention of Cardiovascular Disease Do Not Meet Health Literacy Needs: A Systematic Environmental Scan and Evaluation. International Journal of Environmental Research and Public Health, 19(18). [More Information]
- Bursill, C., Smith, N., Palpant, N., Tan, I., Sunde, M., Harvey, R., Lewis, B., Figtree, G., Vandenberg, J. (2022). Don't Turn Off the Tap! The Importance of Discovery Science to the Australian Cardiovascular Sector and Improving Clinical Outcomes Into the Future. Heart, Lung, and Circulation, 31(10), 1321-1332. [More Information]
- Li, J., Arnott, C., Heerspink, H., Mbiostat, Q., Cannon, C., Wheeler, D., Charytan, D., Barraclough, J., Figtree, G., Agarwal, R., Neal, B., Jardine, M., et al (2022). Effect of Canagliflozin on Total Cardiovascular Burden in Patients With Diabetes and Chronic Kidney Disease: A Post Hoc Analysis From the CREDENCE Trial. Journal of the American Heart Association, 11(16). [More Information]
- Yu, J., Li, J., Leaver, P., Arnott, C., Huffman, M., Udell, J., Perkovic, V., Mahaffey, K., de Zeeuw, D., Fulcher, G., Neal, B., Figtree, G., et al (2022). Effects of canagliflozin on myocardial infarction: a post hoc analysis of the CANVAS programme and CREDENCE trial. Cardiovascular Research, 118(4), 1103-1114. [More Information]
- Kavurma, M., Bursill, C., Stanley, C., Passam, F., Cartland, S., Patel, S., Loa, J., Figtree, G., Golledge, J., Aitken, S., et al (2022). Endothelial cell dysfunction: Implications for the pathogenesis of peripheral artery disease. Frontiers in Cardovascular Medicine, 9. [More Information]
- Sharma, P., Beck, D., Murtha, L., Figtree, G., Boyle, A., Gentile, C. (2022). Fibulin-3 Deficiency Protects Against Myocardial Injury Following Ischaemia/ Reperfusion in in vitro Cardiac Spheroids. Frontiers in Cardovascular Medicine, 9. [More Information]
- Swaraj, S., Kozor, R., Arnott, C., Di Bartolo, B., Figtree, G. (2022). Heart Failure with Reduced Ejection Fraction—Does Sex Matter? Current Heart Failure Reports, 18(6), 345-352. [More Information]
- Hansen, T., Bubb, K., Schiattarella, G., Ugander, M., Tan, T., Figtree, G. (2022). High-Resolution Transthoracic Echocardiography Accurately Detects Pulmonary Arterial Pressure and Decreased Right Ventricular Contractility in a Mouse Model of Pulmonary Fibrosis and Secondary Pulmonary Hypertension. Journal of the American Heart Association, 11(23). [More Information]
- Figtree, G., Kovacic, J., McGuire, H. (2022). Human susceptibility to coronary artery disease: lessons from chimpanzee resilience. Nature Reviews Cardiology, 19(8), 497-498. [More Information]
- Vernon, S., Kott, K., Hansen, T., Finemore, M., Baumgart, K., Bhindi, R., Yang, J., Hansen, P., Nicholls, S., Celermajer, D., Ward, M., Van Nunen, S., Grieve, S., Figtree, G. (2022). Immunoglobulin E Sensitization to Mammalian Oligosaccharide Galactose-á-1,3 (á-Gal) Is Associated With Noncalcified Plaque, Obstructive Coronary Artery Disease, and ST-Segment-Elevated Myocardial Infarction. Arteriosclerosis, Thrombosis, and Vascular Biology, 42(3), 352-361. [More Information]
- Nolde, J., Hillis, G., Atkins, E., Von Huben, A., Marschner, S., Chan, J., Reid, C., Nelson, M., Figtree, G., Chalmers, J., Usherwood, T., Chow, C., et al (2022). Impact of various night-time period definitions on nocturnal ambulatory blood pressure. Journal of Hypertension, 40(11), 2271-2279. [More Information]
- Mujwara, D., Henno, G., Vernon, S., Peng, S., Di Domenico, P., Schroeder, B., Busby, G., Figtree, G., Bottà, G. (2022). Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk-Enhancing Factor in the Pooled Cohort Equation: A Cost-Effectiveness Analysis Study. Journal of the American Heart Association, 11(12). [More Information]
- Figtree, G., Vernon, S., Hadziosmanovic, N., Sundström, J., Alfredsson, J., Nicholls, S., Chow, C., Psaltis, P., Rosjo, H., Leosdottir, M., et al (2022). Mortality and Cardiovascular Outcomes in Patients Presenting With Non–ST Elevation Myocardial Infarction Despite No Standard Modifiable Risk Factors: Results From the SWEDEHEART Registry. Journal of the American Heart Association, 11(15). [More Information]
- Moledina, S., Kobo, O., Lakhani, H., Abhishek, A., Parwani, P., Santos Volgman, A., Bond, R., Rashid, M., Figtree, G., Mamas, M. (2022). Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. IJC Heart & Vasculature, 43. [More Information]
- Figtree, G., Adamson, P., Antoniades, C., Blumenthal, R., Blaha, M., Budoff, M., Celermajer, D., Chan, M., Chow, C., Dey, D., Giannotti, N., Grieve, S., Patel, S., Vernon, S., et al (2022). Noninvasive Plaque Imaging to Accelerate Coronary Artery Disease Drug Development. Circulation, 146(22), 1712-1727. [More Information]
- Kozor, R., Mooney, J., Lowe, H., Kritharides, L., Altman, M., Klimis, H., Thakkar, J., Wynne, D., Thiagalingam, A., Figtree, G., Chow, C. (2022). Rapid Access Chest Pain Clinics: An Australian Cost-Benefit Study. Heart, Lung, and Circulation, 31(2), 177-182. [More Information]
- Ekmejian, A., Bhindi, R., Figtree, G. (2022). Sublingual Nitrates for Patients as a Default in the Post-ACS Discharge Pack: Is It Time for a Rethink? Circulation, 145(11), 791-792. [More Information]
- Figtree, G., Vernon, S., Nicholls, S. (2022). Taking the next steps to implement polygenic risk scoring for improved risk stratification and primary prevention of coronary artery disease. European Journal of Preventive Cardiology, 29(4), 580-587. [More Information]
- Coorey, G., Figtree, G., Fletcher, D., Snelson, V., Vernon, S., Winlaw, D., Grieve, S., McEwan, A., Yang, J., Qian, P., Orchard, J., Kim, J., Patel, S., Redfern, J., et al (2022). The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field. npj Digital Medicine, 5(1), 1-12. [More Information]
- Chin, Y., Ng, C., Chew, N., Kong, G., Lim, W., Tan, D., Chan, K., Tang, A., Huang, D., Chan, M., Figtree, G., et al (2022). The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis. EClinicalMedicine, 54. [More Information]
- Saleh, S., George, J., Kott, K., Meikle, P., Figtree, G. (2022). The Translation and Commercialisation of Biomarkers for Cardiovascular Disease—A Review. Frontiers in Cardovascular Medicine, 9. [More Information]
- May, L., Bartolo, B., Harrison, D., Guzik, T., Drummond, G., Figtree, G., Ritchie, R., Rye, K., De Haan, J. (2022). Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery. Clinical Science, 136(23), 1731-1758. [More Information]
- Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions. Circulation, 144(2), 159-169. [More Information]
- Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A call to action for new global approaches to cardiovascular disease drug solutions. European Heart Journal, 42(15), 1464-1475. [More Information]
- Kim, T., Tang, O., Vernon, S., Kott, K., Koay, Y., Park, J., James, D., Grieve, S., Speed, T., Yang, P., Figtree, G., John, O., Yang, J. (2021). A hierarchical approach to removal of unwanted variation for large-scale metabolomics data. Nature Communications, 12(1), 4992-1-4992-10. [More Information]
- Paige, E., Doyle, K., Jorm, L., Banks, E., Hsu, M., Nedkoff, L., Briffa, T., Cadilhac, D., Mahoney, R., Verjans, J., Figtree, G., et al (2021). A Versatile Big Data Health System for Australia: Driving Improvements in Cardiovascular Health. Heart, Lung, and Circulation, 30(10), 1467-1476. [More Information]
- Kott, K., Morel-Kopp, M., Vernon, S., Takagi, Y., Di Bartolo, B., Peter, K., Yang, J., Grieve, S., Ward, C., Figtree, G. (2021). Association of global coagulation profiles with cardiovascular risk factors and atherosclerosis: A sex disaggregated analysis from the bioheart-ct study. Journal of the American Heart Association, 10(20), e020604. [More Information]
- Alsaigh, T., Di Bartolo, B., Mulangala, J., Figtree, G., Leeper, N. (2021). Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circulation Research, 128(12), 1927-1943. [More Information]
- Bubb, K., Ravindran, D., Cartland, S., Finemore, M., Clayton, Z., Tsang, M., Tang, O., Kavurma, M., Patel, S., Figtree, G. (2021). beta (3) Adrenergic Receptor Stimulation Promotes Reperfusion in Ischemic Limbs in a Murine Diabetic Model. Frontiers in Pharmacology, 12, 666334. [More Information]
- Ciofani, J., Ozorio, G., Don, G., Bernard, E., Figtree, G., Nelson, G. (2021). Cardiac Sarcoidosis Presenting as Cardiogenic Shock and Ventricular Tachycardia. Heart, Lung, and Circulation, 30(10), e112-e114. [More Information]
- Yu, J., Arnott, C., Neuen, B., Heersprink, H., Mahaffey, K., Cannon, C., Khan, S., Baldridge, A., Shah, S., Huang, Y., Figtree, G., Neal, B., et al (2021). Cardiovascular and renal outcomes with canagliflozin according to baseline diuretic use: a post hoc analysis from the CANVAS Program. ESC Heart Failure, 8(2), 1482-1493. [More Information]
- Geraghty, L., Figtree, G., Schutte, A., Patel, S., Woodward, M., Arnott, C. (2021). Cardiovascular Disease in Women: From Pathophysiology to Novel and Emerging Risk Factors. Heart, Lung, and Circulation, 30(1), 9-17. [More Information]
- Tam, C., Gullick, J., Saavedra, A., Vernon, S., Figtree, G., Chow, C., Cretikos, M., Morris, R., William, M., Morris, J., et al (2021). Combining structured and unstructured data in EMRs to create clinically-defined EMR-derived cohorts. BMC Medical Informatics and Decision Making, 21(1), 91. [More Information]
- Sharma, P., Wang, X., Ming, C., Vettori, L., Figtree, G., Boyle, A., Gentile, C. (2021). Considerations for the Bioengineering of Advanced Cardiac In Vitro Models of Myocardial Infarction. Small, 17(15), 2003765. [More Information]
- Vernon, S., Kott, K., Hansen, T., Zhang, K., Cole, B., Coffey, S., Grieve, S., Figtree, G. (2021). Coronary artery disease burden in women poorly explained by traditional risk factors: Sex disaggregated analyses from the BioHEART-CT study. Atherosclerosis, 333, 100-107. [More Information]
- Avis, S., Vernon, S., Hagström, E., Figtree, G. (2021). Coronary artery disease in the absence of traditional risk factors: a call for action. European Heart Journal, 42(37), 3822-3824. [More Information]
- Figtree, G., Vernon, S. (2021). Coronary artery disease patients without standard modifiable risk factors (SMuRFs)- a forgotten group calling out for new discoveries. Cardiovascular Research, 117(6), e76-e78. [More Information]
- Playford, D., Hamilton-Craig, C., Dwivedi, G., Figtree, G. (2021). Examining the Potential for Coronary Artery Calcium (CAC) Scoring for Individuals at Low Cardiovascular Risk. Heart, Lung, and Circulation, 30(12), 1819-1828. [More Information]
- Bubb, K., Tang, O., Gentile, C., Moosavi, S., Hansen, T., Liu, C., Di Bartolo, B., Figtree, G. (2021). FXYD1 Is Protective Against Vascular Dysfunction. Hypertension, 77(6), 2104-2116. [More Information]
- Astell-Burt, T., Navakatikyan, M., Walsan, R., Davis, W., Figtree, G., Arnolda, L., Feng, X. (2021). Green space and cardiovascular health in people with type 2 diabetes. Health & Place, 69, 102554. [More Information]
- Agarwal, A., Peters, S., Chandramouli, C., Lam, C., Figtree, G., Arnott, C. (2021). Guideline-Directed Medical Therapy in Females with Heart Failure with Reduced Ejection Fraction. Current Heart Failure Reports, 18(5), 284-289. [More Information]
- Vernon, S., Tang, O., Kim, T., Chan, A., Kott, K., Park, J., Hansen, T., Koay, Y., Grieve, S., O'Sullivan, J., Yang, J., Figtree, G. (2021). Metabolic Signatures in Coronary Artery Disease: Results from the BioHEART-CT Study. Cells, 10(5), 980. [More Information]
- Figtree, G., Vernon, S., Hadziosmanovic, N., Sundström, J., Alfredsson, J., Arnott, C., Delatour, V., Leósdóttir, M., Hagström, E. (2021). Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data. The Lancet, 397(10279), 1085-1094. [More Information]
- Yousefi-Koma, A., Naghashzadeh, F., Figtree, G., Patel, S., Karimi Galougahi, K. (2021). Multi-modality imaging of inflammation and ischemia for assessment of myocardial injury in Covid-19. Journal of Nuclear Cardiology, 28(6), 3100-3103. [More Information]
- Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A., Malle, E., Bartels, E., Christoffersen, C., Grieve, S., Figtree, G., Davies, M., et al (2021). Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia–reperfusion injury in rats. Scientific Reports, 11(1), 12712-1-12712-18. [More Information]
- Besnier, M., Finemore, M., Yu, C., Kott, K., Vernon, S., Seebacher, N., Genetzakis, E., Furman, A., Tang, O., Davis, R., Hansen, T., Bubb, K., Wise, S., Grieve, S., Di Bartolo, B., Figtree, G., et al (2021). Patient endothelial colony-forming cells to model coronary artery disease susceptibility and unravel the role of dysregulated mitochondrial redox signalling. Antioxidants, 10(10), 1547. [More Information]
- Agbaedeng, T., Noubiap, J., Mofo Mato, E., Chew, D., Figtree, G., Said, M., van der Harst, P. (2021). Polygenic risk score and coronary artery disease: A meta-analysis of 979,286 participant data. Atherosclerosis, 333, 48-55. [More Information]
- Bubb, K., Harmer, J., Finemore, M., Aitken, S., Ali, Z., Billot, L., Chow, C., Golledge, J., Mister, R., Gray, M., Grieve, S., Keech, A., Patel, S., Figtree, G., et al (2021). Protocol for the Stimulating β3- Adrenergic Receptors for Peripheral Artery Disease (STAR- PAD) trial: a double- blinded, randomised, placebo- controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease. BMJ Open, 11(9), e049858-1-e049858-10. [More Information]
- Arnott, C., Li, J., Cannon, C., de Zeeuw, D., Neuen, B., Heerspink, H., Charytan, D., Agarwal, A., Huffman, M., Figtree, G., Jardine, M., et al (2021). The effects of canagliflozin on heart failure and cardiovascular death by baseline participant characteristics: Analysis of the CREDENCE trial. Diabetes, Obesity and Metabolism, 23(7), 1652-1659. [More Information]
- Coorey, G., Figtree, G., Fletcher, D., Redfern, J. (2021). The health digital twin: advancing precision cardiovascular medicine. Nature Reviews Cardiology, 18(12), 803-804. [More Information]
- Vogel, B., Acevedo, M., Appelman, Y., Bairey Merz, C., Chieffo, A., Figtree, G., Guerrero, M., Kunadian, V., Lam, C., Maas, A., Mihailidou, A., et al (2021). The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030. The Lancet, 397(10292), 2385-2438. [More Information]
- Kurup, R., Galougahi, K., Figtree, G., Misra, A., Patel, S. (2021). The Role of Colchicine in Atherosclerotic Cardiovascular Disease. Heart, Lung, and Circulation, 30(6), 795-806. [More Information]
- Hure, A., Ramanathan, S., Deeming, S., Figtree, G., Jennings, G., Webster, J., Morton, R., Redfern, J., Doyle, K., Nicholls, S., et al (2021). Translation and Impact of Funded Australian Cardiovascular Research: A Review With Perspective. Heart, Lung, and Circulation, 30(10), 1442-1448. [More Information]
- Zannad, F., Cotter, G., Alonso Garcia, A., George, S., Davison, B., Figtree, G., Prasad, K., Rockhold, F., Schilsky, R., Stockbridge, N., et al (2021). What can heart failure trialists learn from oncology trialists? European Heart Journal, 42(24), 2373-2383. [More Information]
- Barraclough, J., Harmer, J., Yu, J., Figtree, G., Arnott, C. (2021). Why Are We Forgetting Patients With Peripheral Arterial Disease? Heart, Lung, and Circulation, 30(7), 939-942. [More Information]
- Lembo, R., Gullick, J., Chow, C., Figtree, G., Kozor, R. (2020). A Study of Patient Satisfaction and Uncertainty in a Rapid Access Chest Pain Clinic. Heart, Lung, and Circulation, 29(8), e210-e216. [More Information]
- Redfern, J., Figtree, G., Chow, C., Jennings, G., Briffa, T., Gallagher, R., Foreman, R. (2020). Cardiac Rehabilitation and Secondary Prevention Roundtable: Australian Implementation and Research Priorities. Heart, Lung, and Circulation, 29(3), 319-323. [More Information]
- Allahwala, U., Weaver, J., Nelson, G., Nour, D., Ray, M., Ciofani, J., Ward, M., Figtree, G., Hansen, P., Bhindi, R. (2020). Effect of Recruitment of Acute Coronary Collaterals on In-Hospital Mortality and on Left Ventricular Function in Patients Presenting With ST Elevation Myocardial Infarction. American Journal of Cardiology, 125(10), 1455-1460. [More Information]
- Moon, J., Augusto, J., Menacho, K., Andiapen, M., Bowles, R., Burton, M., Welch, S., Bhuva, A., Seraphim, A., Pade, C., Figtree, G., et al (2020). Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19. Wellcome Open Research, 5, 179. [More Information]
- Climie, R., Wu, J., Calkin, A., Chapman, N., Inglis, S., Mirabito Colafella, K., Picone, D., Tan, J., Thomas, E., Viola, H., Wise, S., Figtree, G., et al (2020). Lack of Strategic Funding and Long-Term Job Security Threaten to Have Profound Effects on Cardiovascular Researcher Retention in Australia. Heart, Lung, and Circulation, 29, 1588-1595. [More Information]
- Li, J., Woodward, M., Perkovic, V., Figtree, G., Heerspink, H., Mahaffey, K., de Zeeuw, D., Vercruysse, F., Shaw, W., Matthews, D., Neal, B. (2020). Mediators of the Effects of Canagliflozin on Heart Failure in Patients With Type 2 Diabetes. JACC: Heart Failure, 8(1), 57-66. [More Information]
- Bubb, K., Drummond, G., Figtree, G. (2020). New opportunities for targeting redox dysregulation in cardiovascular disease. Cardiovascular Research, 116(3), 532-544. [More Information]
- Thavapalachandran, S., Grieve, S., Hume, R., Le, T., Raguram, K., Hudson, J., Pouliopoulos, J., Figtree, G., Dye, R., Barry, A., Coffey, S., Rashid, F., Kizana, E., Asli, N., Chong, J., et al (2020). Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction. Science Translational Medicine, 12(524), 1-11. [More Information]
- Mazhar, J., Figtree, G., Vernon, S., Karimi Galougahi, K., Carlo, J., Nissen, S., Nicholls, S. (2020). Progression of coronary atherosclerosis in patients without standard modifiable risk factors. American Journal of Preventive Cardiology, 4. [More Information]
- Kott, K., Vernon, S., Hansen, T., De Dreu, M., Das, S., Powell, J., Fazekas de St Groth, B., Di Bartolo, B., McGuire, H., Figtree, G. (2020). Single-Cell Immune Profiling in Coronary Artery Disease: The Role of State-of-the-Art Immunophenotyping With Mass Cytometry in the Diagnosis of Atherosclerosis. Journal of the American Heart Association, 9(24), e017759. [More Information]
- Ritchie, R., Karimigalougahi, K., Figtree, G. (2020). Targeting longevity genes in the battle against diabetic heart disease – is there a gene delivery fountain of youth? European Journal of Heart Failure, 22(9), 1582-1585. [More Information]
- Arnott, C., Neuen, B., Heerspink, H., Figtree, G., Kosiborod, M., Lam, C., Cannon, C., Rosenthal, N., Shaw, W., Mahaffey, K., Neal, B., et al (2020). The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program. International Journal of Cardiology, 318, 126-129. [More Information]
- Hansen, T., Galougahi, K., Besnier, M., Genetzakis, E., Tsang, M., Finemore, M., O'Brien-Brown, J., Di Bartolo, B., Kassiou, M., Bubb, K., Figtree, G. (2020). The Novel P2X7 Receptor PKT100 Improves Right Ventricular Function and Survival in Pulmonary Hypertension. American Journal of Physiology - Heart and Circulatory Physiology, 319(1), H183-H191. [More Information]
- Bell, J., Figtree, G., Drummond, G. (2020). Using machine learning to ace cardiovascular risk tests. Cardiovascular Research, 116(14), 2173-2174. [More Information]
- Vijapurapu, R., Kozor, R., Hughes, D., Woolfson, P., Jovanovic, A., Deegan, P., Rusk, R., Figtree, G., Tchan, M., Whalley, D., et al (2019). A randomised controlled trial evaluating arrhythmia burden, risk of sudden cardiac death and stroke in patients with Fabry disease: the role of implantable loop recorders (RaILRoAD) compared with current standard practice. Trials, 20(1), 1-10. [More Information]
- Callaghan, F., Bannon, P., Barin, E., Celermajer, D., Jeremy, R., Figtree, G., Grieve, S. (2019). Age-related changes of shape and flow dynamics in healthy adult aortas: A 4D flow MRI study. Journal of Magnetic Resonance Imaging, 49(1), 90-100. [More Information]
- Kott, K., Vernon, S., Hansen, T., Yu, C., Bubb, K., Coffey, S., Sullivan, D., Yang, J., O'Sullivan, J., Chow, C., Patel, S., Chong, J., Celermajer, D., Kritharides, L., Grieve, S., Figtree, G. (2019). Biobanking for discovery of novel cardiovascular biomarkers using imaging-quantified disease burden: protocol for the longitudinal, prospective, BioHEART-CT cohort study. BMJ Open, 9(9), 1-9. [More Information]
- Climie, R., Kingwell, B., Figtree, G. (2019). Building an Academic-Industry Partnership to Tackle Australia's Biggest Health Burden. Heart, Lung, and Circulation, 28(8), 1144-1147. [More Information]
- Zbinden, R., Wollmann, C., Brachmann, J., Michaelsen, J., Steinwender, C., Kovoor, P., Kelle, S., McGavigan, A., Ching, C., Figtree, G., et al (2019). Clinical safety of the ProMRI implantable cardioverter-defibrillator systems during head and lower lumbar magnetic resonance imaging at 3 T: Results of the ProMRI 3T ENHANCED Master study. Europace, 21(11), 1678-1685. [More Information]
- Gallagher, R., Chow, C., Parker, H., Neubeck, L., Celermajer, D., Redfern, J., Tofler, G., Buckley, T., Schumacher, T., Ferry, C., Whitley, A., Figtree, G., et al (2019). Design and rationale of the MyHeartMate study: a randomised controlled trial of a game-based app to promote behaviour change in patients with cardiovascular disease. BMJ Open, 9(5), 1-7. [More Information]
- Figtree, G., Radholm, K., Barrett, T., Perkovic, V., Mahaffey, K., de Zeeuw, D., Fulcher, G., Matthews, D., Shaw, W., Neal, B. (2019). Effects of Canagliflozin on Heart Failure Outcomes Associated with Preserved and Reduced Ejection Fraction in Type 2 Diabetes: Results from the CANVAS Program. Circulation, 139(22), 2591-2593. [More Information]
- Li, M., Wang, A., Quek, L., Vernon, S., Figtree, G., Yang, J., O'Sullivan, J. (2019). Metabolites downstream of predicted loss-of-function variants inform relationship to disease. Molecular Genetics and Metabolism, 128(4), 476-482. [More Information]
- Bubb, K., Ritchie, R., Figtree, G. (2019). Modified redox signalling in vasculature after chronic infusion of the insulin receptor antagonist, S961. Microcirculation, 26(2), 1-10. [More Information]
- Figtree, G., Radholm, K., Neal, B. (2019). Response by Figtree et al to Letter Regarding Article, Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study)"". Circulation, 139(3), 418-419. [More Information]
- Rowell, A., Stedman, W., Janin, P., Diel, N., Ward, M., Kay, S., Delaney, A., Figtree, G. (2019). Silent left ventricular apical ballooning and Takotsubo cardiomyopathy in an Australian intensive care unit. ESC Heart Failure, 6(6), 1262-1265. [More Information]
- Vernon, S., Coffey, S., D’Souza, M., Chow, C., Kilian, J., Hyun, K., Shaw, J., Adams, M., Roberts-Thomson, P., Brieger, D., Figtree, G. (2019). ST-Segment-Elevation Myocardial Infarction (STEMI) Patients Without Standard Modifiable Cardiovascular Risk Factors-How Common Are They, and What Are Their Outcomes? Journal of the American Heart Association, 8(21), 1-11. [More Information]
- Campbell, M., Chabria, M., Figtree, G., Polonchuk, L., Gentile, C. (2019). Stem Cell-Derived Cardiac Spheroids as 3D In Vitro Models of the Human Heart Microenvironment. Methods in Molecular Biology, 2002, 51-59. [More Information]
- Arnott, C., Parsonage, W., Figtree, G. (2019). Tackling Disparities in Heart Care and Disease Outcomes in Women: Insights and Highlights From the Women and Heart Disease Forum. Heart, Lung, and Circulation, 28(10), 1449-1451. [More Information]
- Figtree, G., Bubb, K., Ngo, D. (2019). Testosterone to estradiol ratio and plaque inflammation- mechanistic insights and biomarker potential? Cardiovascular Research, 115(2), 255-257. [More Information]
- Figtree, G., Jennings, G., Nicholls, S., Graham, R. (2019). The Australian Cardiovascular Alliance-Towards an Integrated Whole-of-Nation Strategy to Address Our Major Health Burden. Heart, Lung, and Circulation, 28(2), 198-203. [More Information]
- Vernon, S., Hansen, T., Kott, K., Yang, J., O'Sullivan, J., Figtree, G. (2019). Utilizing state-of-the-art "omics" technology and bioinformatics to identify new biological mechanisms and biomarkers for coronary artery disease. Microcirculation, 26(2), 1-9. [More Information]
- Lawley, C., Broadhouse, K., Callaghan, F., Winlaw, D., Figtree, G., Grieve, S. (2018). 4D flow magnetic resonance imaging: role in pediatric congenital heart disease. Asian Cardiovascular and Thoracic Annals, 26(1), 28-37. [More Information]
- Bonnitcha, P., Grieve, S., Figtree, G. (2018). Clinical imaging of hypoxia: Current status and future directions. Free Radical Biology and Medicine, 126, 296-312. [More Information]
- MacIsaac, A., Figtree, G. (2018). Why are women with ST-elevation myocardial infarction treated differently to men? Medical Journal of Australia, 209(3), 115-116. [More Information]
- Polonchuk, L., Chabria, M., Badi, L., Hofack, J., Figtree, G., Davies, M., Gentile, C. (2017). Cardiac spheroids as promising in vitro models to study the human heart microenvironment. Scientific Reports, 7(1), 1-12. [More Information]
- Mawad, D., Figtree, G., Gentile, C. (2017). Current Technologies Based on the Knowledge of the Stem Cells Microenvironments. Advances in Experimental Medicine and Biology, 1041, 245-262. [More Information]
- Figtree, G., Nelson, G., Bhindi, R. (2017). Festschrift for Professor Stephen Hunyor — Celebrating his Clinical and Scientific Contribution and the Legacy he has Left at Royal North Shore Hospital, and the Broader Cardiovascular Research Community. Heart, Lung, and Circulation, 26(1), 6-9. [More Information]
- O'Neill, E., Kaur, A., Bishop, D., Shishmarev, D., Kuchel, P., Grieve, S., Figtree, G., Renfrew, A., Bonnitcha, P., New, E. (2017). Hypoxia-responsive cobalt complexes in tumor spheroids: Laser ablation inductively coupled plasma mass spectrometry and magnetic resonance imaging studies. Inorganic Chemistry, 56(16), 9860-9868. [More Information]
- Vernon, S., Coffey, S., Bhindi, R., Hoo, S., Nelson, G., Ward, M., Hansen, P., Asrress, K., Chow, C., Celermajer, D., O'Sullivan, J., Figtree, G. (2017). Increasing proportion of ST elevation myocardial infarction patients with coronary atherosclerosis poorly explained by standard modifiable risk factors. European Journal of Preventive Cardiology, 24(17), 1824-1830. [More Information]
- Kozor, R., Nordin, S., Treibel, T., Rosmini, S., Castelletti, S., Fontana, M., Captur, G., Baig, S., Steeds, R., Hughes, D., Grieve, S., Figtree, G., et al (2017). Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping. European Heart Journal - Cardiovascular Imaging, 18, 1034-1040. [More Information]
- Tate, M., Deo, M., Cao, A., Hood, S., Huynh, K., Kiriazis, H., Du, X., Julius, T., Figtree, G., Dusting, G., et al (2017). Insulin replacement limits progression of diabetic cardiomyopathy in the low-dose streptozotocin-induced diabetic rat. Diabetes and Vascular Disease Research, 14(5), 423-433. [More Information]
- Lawley, C., Lain, S., Figtree, G., Sholler, G., Winlaw, D., Roberts, C. (2017). Mortality, rehospitalizations and costs in children undergoing a cardiac procedure in their first year of life in New South Wales, Australia. International Journal of Cardiology, 241, 156-162. [More Information]
- Callaghan, F., Arnott, C., Figtree, G., Kutty, S., Celermajer, D., Grieve, S. (2017). Quantifying right atrial filling and emptying: A 4D-flow MRI study. Journal of Magnetic Resonance Imaging, 45(4), 1046-1054. [More Information]
- Callaghan, F., Arnott, C., Figtree, G., Kutty, S., Celermajer, D., Grieve, S. (2017). Quantifying right atrial filling and emptying: A 4D-flow MRI study. Journal of Magnetic Resonance Imaging, 45(4), 1-1. [More Information]
- Klimis, H., Thiagalingam, A., Altman, M., Atkins, E., Figtree, G., Lowe, H., Cheung, N., Kovoor, P., Denniss, A., Chow, C. (2017). Rapid-access cardiology services: can these reduce the burden of acute chest pain on Australian and New Zealand health services? Internal Medicine Journal, 47(9), 986-991. [More Information]
- Bubb, K., Birgisdottir, A., Tang, O., Hansen, T., Figtree, G. (2017). Redox modification of caveolar proteins in the cardiovascular system- role in cellular signalling and disease. Free Radical Biology and Medicine, 109, 61-74. [More Information]
- Bubb, K., Kok, C., Tang, O., Rasko, N., Birgisdottir, A., Hansen, T., Ritchie, R., Bhindi, R., Reisman, S., Meyer, C., Karimigalougahi, K., Figtree, G., et al (2017). The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling. Free Radical Biology and Medicine, 108, 585-594. [More Information]
- Figtree, G., Bubb, K., Tang, O., Kizana, E., Gentile, C. (2017). Vascularized Cardiac Spheroids as Novel 3D in vitro Models to Study Cardiac Fibrosis. Cells Tissues Organs, 204(3-Apr), 191-198. [More Information]
- Jiang, L., Gentile, C., Lauto, A., Cui, C., Song, Y., Romeo, T., Silva, S., Tang, O., Sharma, P., Figtree, G., et al (2017). Versatile Fabrication Approach of Conductive Hydrogels via Copolymerization with Vinyl Monomers. ACS Applied Materials and Interfaces, 9(50), 44124-44133. [More Information]
- Ngo, D., Roberts, C., Figtree, G. (2016). Association between interpregnancy interval and future risk of maternal cardiovascular disease-a population-based record linkage study. BJOG, 123(8), 1311-1318. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N., Hamilton, E., Hawkins, C., Figtree, G. (2016). Beta3 adrenergic stimulation restores nitric oxide/redox balance and enhances endothelial function in hyperglycemia. Journal of the American Heart Association, 5(2), 1-17. [More Information]
- Kozor, R., Grieve, S., Tchan, M., Callaghan, F., Hamilton-Craig, C., Denaro, C., Moon, J., Figtree, G. (2016). Cardiac involvement in genotype-positive Fabry disease patients assessed by cardiovascular MR. Heart, 102(4), 298-302. [More Information]
- Kozor, R., Grieve, S., Figtree, G., Bhindi, R. (2016). Cardiovascular magnetic resonance, mitral regurgitation and outcomes: the importance of accurate assessment in an era of increasing intervention. Journal of Thoracic Disease, 8(9), E1053-E1056. [More Information]
- Shao, L., Ma, A., Figtree, G., Zhang, P. (2016). Combination Therapy With Coenzyme Q10 and Trimetazidine in Patients With Acute Viral Myocarditis. Journal of Cardiovascular Pharmacology, 68(2), 150-154. [More Information]
- Lyon, A., Bossone, E., Schneider, B., Sechtem, U., Citro, R., Underwood, S., Sheppard, M., Figtree, G., Parodi, G., Akashi, Y., et al (2016). Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 18(1), 8-27. [More Information]
- Evin, M., Broadhouse, K., Callaghan, F., McGrath, R., Glastras, S., Kozor, R., Hocking, S., Lamy, J., Redheuil, A., Kachenoura, N., Fulcher, G., Figtree, G., Grieve, S. (2016). Impact of obesity and epicardial fat on early left atrial dysfunction assessed by cardiac MRI strain analysis. Cardiovascular Diabetology, 15(1), 1-10. [More Information]
- Ngo, A., Roberts, C., Chen, J., Figtree, G. (2016). Interaction of maternal smoking and preterm birth on future risk of maternal cardiovascular disease: A population-based record linkage study. European Journal of Preventive Cardiology, 23(6), 613-620. [More Information]
- Sverdlov, A., Figtree, G., Horowitz, J., Ngo, D. (2016). Interplay between Oxidative Stress and Inflammation in Cardiometabolic Syndrome. Mediators of Inflammation, 2016, 1-3. [More Information]
- Gaikwad, N., Butler, T., Maxwell, R., Shaw, E., Strugnell, W., Chan, J., Figtree, G., Slaughter, R., Hamilton-Craig, C. (2016). Late gadolinium enhancement does occur in Tako-tsubo cardiomyopathy - A quantitative cardiac magnetic resonance and speckle tracking strain study. IJC Heart & Vasculature, 12, 68-74. [More Information]
- Hansen, T., Galougahi, K., Celermajer, D., Rasko, N., Tang, O., Bubb, K., Figtree, G. (2016). Oxidative and Nitrosative Signalling in Pulmonary Arterial Hypertension- Implications for Development of Novel Therapies. Pharmacology & Therapeutics, 165, 50-62. [More Information]
- Oh, B., Figtree, G., Costa, D., Eade, T., Hruby, G., Lim, S., Elfiky, A., Martine, N., Rosenthal, D., Clarke, S., Back, M. (2016). Oxidative stress in prostate cancer patients: A systematic review of case control studies. Prostate International, 4(3), 71-87. [More Information]
- Seneviratne, M., Grieve, S., Figtree, G., Garsia, R., Celermajer, D., Adelstein, S., Puranik, R. (2016). Prevalence, distribution and clinical correlates of myocardial fibrosis in systemic lupus erythematosus: a cardiac magnetic resonance study. Lupus, 25(6), 573-581. [More Information]
- Huang, A., Murphy, J., Shaw, E., Kozor, R., Yan, W., Loxton, A., Soo Hoo, S., Figtree, G., Rasmussen, H., Hansen, P., Nelson, G., Bhindi, R., Ward, M. (2016). Routine aspiration thrombectomy improves the diagnosis and management of embolic myocardial infarction. Catheterization and Cardiovascular Interventions, 87(4), 642-647. [More Information]
- Madan, A., Yan, W., Byrne, P., Ward, M., Hansen, P., Whalley, D., Kanagaratnam, L., Figtree, G. (2016). Significance of left atrial appendage filling defects on cardiac CT prior to pulmonary vein isolation for atrial fibrillation. International Journal of Cardiology, 203, 520-522. [More Information]
- Dona, A., Coffey, S., Figtree, G. (2016). Translational and emerging clinical applications of metabolomics in cardiovascular disease diagnosis and treatment. European Journal of Preventive Cardiology, 23(15), 1578-1589. [More Information]
- Callaghan, F., Kozor, R., Sherrah, A., Vallely, M., Celermajer, D., Figtree, G., Grieve, S. (2016). Use of multi-velocity encoding 4D flow MRI to improve quantification of flow patterns in the aorta. Journal of Magnetic Resonance Imaging, 43(2), 352-363. [More Information]
- Kozor, R., Callaghan, F., Nelson, G., Figtree, G., Grieve, S. (2015). 4D Multi-VENC Cardiac MRI: Characterisation of a Functional Stenosis of the Ascending Aorta. Heart, Lung, and Circulation, 24(11), 1134-1135. [More Information]
- Kozor, R., Callaghan, F., Tchan, M., Hamilton-Craig, C., Figtree, G., Grieve, S. (2015). A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease. Journal of Cardiovascular Magnetic Resonance, 17(1), 1-7. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Fry, N., Hamilton, E., Figtree, G., Rasmussen, H. (2015). Beta3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade. American Journal of Physiology: Cell Physiology, 309(5), C286-C295. [More Information]
- Allahwala, U., Cockburn, J., Shaw, E., Figtree, G., Hansen, P., Bhindi, R. (2015). Clinical utility of optical coherence tomography (OCT) in the optimisation of Absorb bioresorbable vascular scaffold deployment during percutaneous coronary intervention. EuroIntervention, 10(10), 1154-1159. [More Information]
- Mazhar, J., Shaw, E., Allahwala, U., Figtree, G., Bhindi, R. (2015). Comparison of two dimensional quantitative coronary angiography (2D-QCA) with optical coherence tomography (OCT) in the assessment of coronary artery lesion dimensions. IJC Heart & Vasculature, 7, 14-17. [More Information]
- Liang, S., Figtree, G., Aiqun, M., Ping, Z. (2015). GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. Toxicology Letters, 234(3), 162-171. [More Information]
- Liang, S., Aiqun, M., Figtree, G., Ping, Z. (2015). GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury. International Journal of Biological Macromolecules, 81, 375-386. [More Information]
- Cockburn, J., Karimi, K., Hoo, S., Rasmussen, H., Hansen, P., Nelson, G., Ward, M., Bhindi, R., Figtree, G. (2015). Outcomes by Day and Night for Patients Bypassing the Emergency Department Presenting with ST-Segment Elevation Myocardial Infarction Identified with a Pre-Hospital Electrocardiogram. Journal of Interventional Cardiology, 28(1), 24-31. [More Information]
- Karimigalougahi, K., Antoniades, C., Nicholls, S., Channon, K., Figtree, G. (2015). Redox biomarkers in cardiovascular medicine. European Heart Journal, 36(25), 1576-1582. [More Information]
- Gnjidic, D., Naganathan, V., Freedman, S., Beer, C., McLachlan, A., Hilmer, S., Figtree, G. (2015). Statin therapy and cognition in older people: What is the evidence? Current Clinical Pharmacology, 10(3), 185-193. [More Information]
- Chia, K., Liu, C., Hamilton, E., Garcia, A., Fry, N., Hannam, W., Figtree, G., Rasmussen, H. (2015). Stimulation of the cardiac myocyte NA+-K+ pump due to reversal of its constitutive oxidative inhibition. American Journal of Physiology: Cell Physiology, 309(4), C239-C250. [More Information]
- Shaw, E., Allahwala, U., Cockburn, J., Hansen, T., Mazhar, J., Figtree, G., Hansen, P., Bhindi, R. (2015). The effect of coronary artery plaque composition, morphology and burden on Absorb bioresorbable vascular scaffold expansion and eccentricity - A detailed analysis with optical coherence tomography. International Journal of Cardiology, 184(1), 230-236. [More Information]
- Grover, S., Bell, G., Lincoff, A., Jeorg, L., Madsen, P., Huang, S., Leow, S., Figtree, G., Chakrabarty, A., Woodman, R., et al (2015). Utility of CMR Markers of Myocardial Injury in Predicting LV Functional Recovery: Results from PROTECTION AMI CMR sub-study. Heart, Lung, and Circulation, 24(9), 891-897. [More Information]
- Grieve, S., Mazhar, J., Callaghan, F., Kok, C., Tandy, S., Bhindi, R., Figtree, G. (2014). Automated Quantification of Myocardial Salvage in a Rat Model of Ischemia-Reperfusion Injury Using 3D High-Resolution Magnetic Resonance Imaging (MRI). Journal of the American Heart Association, 3(4), 1-11. [More Information]
- Murphy, J., Hansen, P., Bhindi, R., Figtree, G., Nelson, G., Ward, M. (2014). Cost Benefit for Assessment of Intermediate Coronary Stenosis with Fractional Flow Reserve in Public and Private Sectors in Australia. Heart, Lung, and Circulation, 23(9), 807-810. [More Information]
- Kozor, R., Pollock, C., Gill, A., Bhindi, R., Figtree, G. (2014). Fabry disease deposition mimicking a cardiac tumour and precipitating heart block. European Heart Journal - Cardiovascular Imaging, 15(8), 869-869. [More Information]
- Karimigalougahi, K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N., Davies, M., Hawkins, C., Rasmussen, H., Figtree, G. (2014). Glutathionylation Mediates Angiotension II-Induced eNOS Uncoupling, Amplifying NADPH Oxidase-Dependent Endothelial Dysfunction. Journal of the American Heart Association, 3(2), 1-11. [More Information]
- Lawley, C., Algert, C., Ford, J., Nippita, T., Figtree, G., Roberts, C. (2014). Heart Valve Prostheses in Pregnancy: Outcomes for Women and Their Infants. Journal of the American Heart Association, 3(3), 1-8. [More Information]
- Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2014). Prosthetic heart valves in pregnancy: a systematic review and meta-analysis protocol. Systematic Reviews, 3, 1-7. [More Information]
- Kozor, R., Grieve, S., Buchholz, S., Kaye, S., Darke, S., Bhindi, R., Figtree, G. (2014). Regular Cocaine Use Is Associated with Increased Systolic Blood Pressure, Aortic Stiffness and Left Ventricular Mass in Young Otherwise Healthy Individuals. PloS One, 9(4), 1-8. [More Information]
- Ho, E., Karimigalougahi, K., Liu, C., Bhindi, R., Figtree, G. (2013). Biological markers of oxidative stress: Applications to cardiovascular research and practice. Redox Biology, 1(1), 483-491. [More Information]
- Grieve, S., Lonborg, J., Mazhar, J., Tan, T., Ho, E., Liu, C., Lay, W., Gill, A., Kuchel, P., Bhindi, R., Figtree, G. (2013). Cardiac magnetic resonance imaging of rapid VCAM-1 up-regulation in myocardial ischemia-reperfusion injury. European Biophysics Journal, 42(1), 61-70. [More Information]
- McMahon, R., Siow, W., Bhindi, R., Hoo, S., Figtree, G., Hansen, P., Nelson, G., Rasmussen, H., Ward, M. (2013). Left bundle branch block without concordant ST changes is rarely associated with acute coronary occlusion. International Journal of Cardiology, 167(4), 1339-1342. [More Information]
- Figtree, G., Bagnall, R., Abdulla, I., Buchholz, S., Karimigalougahi, K., Yan, W., Tan, T., Neil, C., Horowitz, J., Semsarian, C., Ward, M. (2013). No association of G-protein-coupled receptor kinase 5 or β-adrenergic receptor polymorphisms with Takotsubo cardiomyopathy in a large Australian cohort. European Journal of Heart Failure, 15(7), 730-733. [More Information]
- Mazhar, J., Murphy, J., Figtree, G., Hansen, P., Nelson, G., Bhindi, R. (2013). Optical coherence tomography (OCT) as an adjunct to percutaneous coronary intervention; a single centre experience. International Journal of Cardiology, 163(3), e49-e52. [More Information]
- Kanagaratnam, L., Lee, A., Whalley, D., Figtree, G. (2013). Overcoming Artifacts and Fears: Electrophysiology Study and Radiofrequency Ablation in a Parkinsonian Patient with Supraventricular Tachycardia and a Brain Neurostimulator. Pacing And Clinical Electrophysiology, 36(1), 1-3. [More Information]
- Liu, C., Karimigalougahi, K., Weisbrod, R., Hansen, T., Ravaie, R., Nunez, A., Liu, Y., Fry, N., Garcia, A., Hamilton, E., Figtree, G., et al (2013). Oxidative inhibition of the vascular Na+-K+ pump via NADPH oxidase-dependent β1-subunit glutathionylation: Implications for angiotensin II-induced vascular dysfunction. Free Radical Biology and Medicine, 65(2013), 563-572. [More Information]
- Figtree, G., Rasmussen, H., Liu, C. (2013). Oxidative regulation of the na+-k+ pump in cardiac physiology and pathology: clarifying the published evidence. Circulation Research, 112(1), e1-e1. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Fry, N., Hamilton, E., Rasmussen, H., Figtree, G. (2013). Protein kinase-dependent oxidative regulation of the cardiac Na+-K+ pump: evidence from in vivo and in vitro modulation of cell signalling. Journal of Physiology, 591(12), 2999-3015. [More Information]
- Liu, C., Fry, N., Hamilton, E., Chia, K., Garcia, A., Karimigalougahi, K., Figtree, G., Clarke, R., Bundgaard, H., Rasmussen, H. (2013). Redox-dependent regulation of the Na+ -K+ pump: New twists to an old target for treatment of heart failure. Journal of Molecular and Cellular Cardiology, 61, 94-101. [More Information]
- Rayner, B., Figtree, G., Sabaretnam, T., Shang, P., Mazhar, J., Weaver, J., Lay, W., Witting, P., Hunyor, S., Grieve, S., Bhindi, R., et al (2013). Selective Inhibition of the Master Regulator Transcription Factor Egr-1 With Catalytic Oligonucleotides Reduces Myocardial Injury and Improves Left Ventricular Systolic Function in a Preclinical Model of Myocardial Infarction. Journal of the American Heart Association, 2(4), 1-9. [More Information]
- Puckeridge, M., Chapman, B., Conigrave, A., Grieve, S., Figtree, G., Kuchel, P. (2013). Stoichiometric relationship between Na+ ions transported and glucose consumed in human erythrocytes: Bayesian analysis of 23Na and 13C NMR time course data. Biophysical Journal, 104(8), 1676-1684. [More Information]
- Figtree, G., Bhindi, R., Cockburn, J., Wilkes, N., Ward, M., Hansen, P. (2013). Use of optical coherence tomography to guide treatment of an undeployed stent trapped in the right coronary artery to cover a proximal stent outflow dissection. International Journal of Cardiology, 167, e163-e166. [More Information]
- Lonborg, J., Ward, M., Gill, A., Grieve, S., Figtree, G. (2013). Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis. BMC Medical Imaging, 13(1), 1-5. [More Information]
- Mazhar, J., Lawley, C., Gill, A., Grieve, S., Figtree, G. (2013). Visualizing pericardial inflammation as the cause of acute chest pain in a patient with a congenital pericardial cyst: the incremental diagnostic value of cardiac magnetic resonance. European Heart Journal, 34(19), 1413-1413. [More Information]
- Lawley, C., Mazhar, J., Grieve, S., Figtree, G. (2013). Visualizing pericardial inflammation in Dressler's syndrome with cardiac magnetic resonance imaging. International Journal of Cardiology, 168(1), e32-e33. [More Information]
- Lay, W., Rayner, B., Sabaretnam, T., Figtree, G., Jackson, C., Hunyor, S., Bhindi, R. (2012). Activated protein C improves left ventricular remodelling after ischemia-reperfusion injury in rats. International Journal of Cardiology, 159(3), 246-248. [More Information]
- Huang, A., Mathur, M., Figtree, G. (2012). Cardiac magnetic resonance characterization of an iatrogenic left ventricular apical pseudo- aneurysm. European journal of Echocardiography, 13(12), 1000-1000. [More Information]
- Buchholz, S., Shakil, A., Figtree, G., Hansen, P., Bhindi, R. (2012). Diagnosis and management of patent foramen ovale. Postgraduate Medical Journal, 88(1038), 217-225. [More Information]
- Kozor, R., Nelson, G., Figtree, G. (2012). Extensive mid-wall myocardial oedema after aborted sudden death in hypertrophic cardiomyopathy. International Journal of Cardiology, 154(1), e14-e15. [More Information]
- Ward, M., Figtree, G. (2012). Letter by Ward and Figtree article, "mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease". Circulation, 126(6), e82-e82. [More Information]
- Yan, W., Nelson, G., Figtree, G., Bhindi, R. (2012). Overcoming Limited Depth Penetration of Optical Coherence Tomography With Wire Bias. J A C C: Cardiovascular Interventions, 5(1), e1-e2. [More Information]
- Figtree, G., Karimigalougahi, K., Liu, C., Rasmussen, H. (2012). Oxidative regulation of the Na+ -K+ pump in the cardiovascular system. Free Radical Biology and Medicine, 53(12), 2263-2268. [More Information]
- Murphy, J., Kozor, R., Figtree, G., Ward, M., Bhindi, R. (2012). Percutaneous coronary intervention via the radial artery: comparison of procedural success in emergency versus non-emergency cases. Cardiovascular Revascularization Medicine, 13(5), 277-280. [More Information]
- Murphy, J., Kozor, R., Figtree, G., Hansen, P., Rasmussen, H., Ward, M., Nelson, G., Bhindi, R. (2012). Procedural and in-patient outcomes in patients aged 80 years or older undergoing contemporary primary percutaneous coronary intervention. EuroIntervention, 8(8), 912-919. [More Information]
- Rowell, A., Figtree, M., Dimmick, S., Kotsiou, G., Grieve, S., Figtree, G. (2012). Recurrent right ventricular echinococcosis characterized by cardiac magnetic resonance. International Journal of Cardiology, 158(2), 293-294. [More Information]
- Fong, L., Mathur, M., Bhindi, R., Figtree, G. (2012). Right atrial Merkel cell tumour metastasis characterization using a multimodality approach. European Heart Journal, 33(17), 2205-2205. [More Information]
- Liu, C., Garcia, A., Mahmmoud, Y., Hamilton, E., Galougahi, K., Fry, N., Figtree, G., Cornelius, F., Clarke, R., Rasmussen, H. (2012). Susceptibility of β1 Na+ -K+ pump subunit to glutathionylation and oxidative inhibition depends on conformational state of pump. Journal of Biological Chemistry, 287(15), 12353-12364. [More Information]
- Figtree, G., Lonborg, J., Grieve, S., Ward, M., Bhindi, R. (2011). Cardiac Magnetic Resonance Imaging for the Interventional Cardiologist. J A C C: Cardiovascular Interventions, 4(2), 137-148. [More Information]
- Hamilton, E., Figtree, G., Rasmussen, H. (2011). Consideration of natriuretic peptide receptor C. Circulation Research, 108(4), e4-e5. [More Information]
- Bibert, S., Liu, C., Figtree, G., Garcia, A., Hamilton, E., Marassi, F., Sweadner, K., Cornelius, F., Geering, K., Rasmussen, H. (2011). FXYD Proteins Reverse Inhibition of the Na+-K+ Pump Mediated by Glutathionylation of Its beta 1 Subunit. Journal of Biological Chemistry, 286(21), 18562-18572. [More Information]
- Ho, E., Bhindi, R., Ashley, E., Figtree, G. (2011). Genetic analysis in cardiovascular disease: a clinical perspective. Cardiology in Review, 19(2), 81-89. [More Information]
- Karimigalougahi, K., Harden, M., Maher, R., Gill, A., Bhindi, R., Grieve, S., Brady, P., Figtree, G. (2011). Incremental Diagnostic Value of Magnetic Resonance Imaging in the Characterization of a Cardiac Mass. Journal of the American College of Cardiology, 58(10), e19-e19. [More Information]
- Bhindi, R., Grieve, S., Figtree, G. (2011). Micromyocardial infarction in apical hypertrophic cardiomyopathy with obliterative coronary artery bridging. International Journal of Cardiology, 151(1), e24-e25. [More Information]
- Yu, C., Grieve, S., Brazier, D., Bhindi, R., Figtree, G. (2011). Post-infarct ventricular thrombus: a critical diagnosis made by cardiac magnetic resonance imaging. Heart, Lung, and Circulation, 20(6), 373-373. [More Information]
- Montfort, J., Maher, R., Grieve, S., Figtree, G. (2011). Syringomyelia: A rare extracardiac contributor to syncope detected incidentally by CMR. International Journal of Cardiology, 150(2), e62-e64. [More Information]
- Yu, C., Brazier, D., Bhindi, R., Figtree, G., Ward, M. (2011). Use of computer tomography coronary angiography in assessment of aorto-ostial coronary disease. International Journal of Cardiology, 147(1), 153-154. [More Information]
- White, C., Liu, C., Garcia, A., Hamilton, E., Chia, K., Figtree, G., Rasmussen, H. (2010). Activation of cAMP-dependent signaling induces oxidative modification of the cardiac Na+-K+ pump and inhibits its activity. Journal of Biological Chemistry, 285(18), 13712-13720. [More Information]
- Robaei, D., Grieve, S., Nelson, G., Figtree, G. (2010). Cocaine-induced epicardial coronary artery thrombosis resulting in extensive myocardial injury assessed by cardiac magnetic resonance imaging. European Heart Journal, 31(20), 2446. [More Information]
- Buchholz, S., Grieve, S., Maher, R., Figtree, G. (2010). Cocaine-induced myocardial injury seen as multiple mid-wall foci of late enhancement by contrast-enhanced cardiac magnetic resonance imaging. European Heart Journal, 31(11), 1422. [More Information]
- Lonborg, J., Mathur, M., Grieve, S., Bhindi, R., Ward, M., Lowe, H., McCrohon, J., Figtree, G. (2010). Constrictive Pericarditis Diagnosed by Cardiac Magnetic Resonance. Journal of the American College of Cardiology, 56(20), e39-e39. [More Information]
- Testa, L., Biondi Zoccai, G., Valgimigli, M., Latini, R., Pizzocri, S., Lanotte, S., Laudisa, M., Brambilla, N., Ward, M., Figtree, G., et al (2010). Current concepts on antiplatelet therapy: focus on the novel thienopyridine and non-thienopyridine agents. Advances in Hematology, 2010, 595934. [More Information]
- Figtree, G., Guzik, T., Robinson, B., Channon, K., Watkins, H. (2010). Functional estrogen receptor alpha promoter polymorphism is associated with improved endothelial-dependent vasolidation. International Journal of Cardiology, 143(2), 207-208. [More Information]
- Grieve, S., Bhindi, R., Seow, J., Doyle, A., Turner, A., Tomka, J., Lay, W., Gill, A., Hunyor, S., Figtree, G. (2010). Microvascular obstruction by intracoronary delivery of mesenchymal stem cells and quantification of resulting myocardial infarction by cardiac magnetic resonance. Circulation. Heart Failure, 3(3), e5-e6. [More Information]
- Rasmussen, H., Liu, C., Figtree, G. (2010). Reversible oxidative modification: implications for cardiovascular physiology and pathophysiology. Trends In Cardiovascular Medicine, 20(3), 85-90. [More Information]
- Figtree, G., Thiruvallapan, N., Brereton, J., Whalley, D., Tofler, G. (2010). The effect of elevated right atrial pressure due to pulmonary emboli on detection of patent foramen ovale and potential paradoxical embolus. Journal of Cardiovascular Medicine (Hagerstown), 11(1), 61-63. [More Information]
- Bundgaard, H., Liu, C., Garcia, A., Hamilton, E., Huang, Y., Chia, K., Hunyor, S., Figtree, G., Rasmussen, H. (2010). {beta}3 Adrenergic Stimulation of the Cardiac Na+-K+ Pump by Reversal of an Inhibitory Oxidative Modification. Circulation, 122, 2699-2708. [More Information]
- White, C., Figtree, G., Liu, C., Garcia, A., Hamilton, E., Chia, K., Rasmussen, H. (2009). Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH oxidase. American Journal of Physiology: Cell Physiology, 296(4), C693-C700. [More Information]
- Figtree, G., Noonan, J., Bhindi, R., Collins, P. (2009). Estrogen Receptor Polymorphisms: Significance to Human Physiology, Disease and Therapy. Recent Patents on DNA and Gene Sequences, , 0. [More Information]
- Bhindi, R., Figtree, G. (2009). Percutaneous coronary intervention versus coronary-artery bypass grafting. New England Journal of Medicine, 360(25), 2672; author reply 2674-5. [More Information]
- Figtree, G., Robinson, B., Channon, K., Watkins, H. (2009). Polymorphism upstream of estrogen receptor alpha reverses negative regulation of transcription. International Journal of Cardiology, 144(1), 86-8. [More Information]
- Figtree, G., Liu, C., Bibert, S., Hamilton, E., Garcia, A., White, C., Chia, K., Cornelius, F., Geering, K., Rasmussen, H. (2009). Reversible oxidative modification: A key mechanism of Na+-K + pump regulation. Circulation Research, 105(2), 185-193. [More Information]
- Rasmussen, H., Figtree, G., Krum, H., Bundgaard, H. (2009). The use of beta3-adrenergic receptor agonists in the treatment of heart failure. Current Opinion in Investigational Drugs (Print), 10(9), 955-962. [More Information]
- Figtree, G., Grieve, S., Speller, B., Geiger, M., Robinson, B., Channon, K., Ragoussis, J., Collins, P., Watkins, H. (2008). A commonly occurring polymorphism upstream of the estrogen receptor alpha alters transcription and is associated with increased HDL. Atherosclerosis, 199(2), 354-361. [More Information]
- William, M., Hamilton, E., Bundgaard, H., Garcia, A., Chia, K., Figtree, G., Rasmussen, H. (2008). Natriuretic peptides stimulate the cardiac sodium pump via NPR-C coupled NOS activation. American Journal of Physiology: Cell Physiology, 294(4), C1067-C1073. [More Information]
- White, C., Hamilton, E., Garcia, A., Wang, D., Chia, K., Figtree, G., Rasmussen, H. (2008). Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes. American Journal of Physiology: Cell Physiology, 294, C572-C578. [More Information]
- Rasmussen, H., Figtree, G. (2007). "Don't flog the heart!" - development of specific drug therapies for heart failure. Critical Care and Resuscitation, 9(4), 364-369. [More Information]
- Goodstadt, L., Powell, T., Figtree, G. (2006). 17β-Estradiol Potentiates the Cardiac Cystic Fibrosis Transmembrane Conductance Regulator Chloride Current in Guinea-pig Ventricular Myocytes. The Journal of Physiological Sciences, 56(1), 29-37. [More Information]
- Figtree, G., Kindmark, A., Lind, L., Grundberg, E., Speller, B., Robinson, B., Channon, K., Watkins, H. (2006). Novel estrogen receptor alpha promoter polymorphism increases ventricular hypertrophic response to hypertension. Journal of Steroid Biochemistry and Molecular Biology, 103(2), 110-118. [More Information]
- Figtree, G., Robinson, B. (2004). Estrogen Receptor Polymorphisms In Common Disease:Recent Developments. Current Opinion in Endocrinology, Diabetes and Obesity, 11(3), 141-146. [More Information]
- Figtree, G., McDonald, D., Watkins, H., Channon, K. (2003). Truncated Estrogen Receptor α 46-kDa Isoform in Human Endothelial Cells: Relationship to Acute Activation of Nitric Oxide Synthase. Circulation, 107(1), 120-126. [More Information]
- Cooper, L., Clifton-Bligh, P., Nery, M., Figtree, G., Twigg, S., Hibbert, E., Robinson, B. (2003). Vitamin D supplementation and bone mineral density in early postmenopausal women. American Journal of Clinical Nutrition, 77(5), 1324-1329.
Conferences
- Neubeck, A., Gallagher, R., Ingram, K., Celermajer, D., Schumacher, T., Ferry, K., Buckley, T., Redfern, J., Chow, C., Tofler, G., Figtree, G. (2016). MyHeartMate: Development of a Digital Game to Improve Secondary Prevention of Cardiovascular Disease. Abstracts for the 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide: Elsevier.
- Figtree, G., Watkins, H., Robinson, B., Channon, K. (2006). Novel polymorphism in estrogen receptor alpha reverses negative transcriptional regulation and is associated with improved endothelial-dependent vasodilation. American Heart Association Annual Scientific Sessions 2005, United States: American Heart Association.
Patents
- Figtree, G., Liu, C., Fry, N., Galougahi, K. (2017). Biomarkers of Oxidative Stress. Patent No. 9,638,699.
Report
- Tam, C., Brieger, D., Gullick, J., Morris, J., Saavedra, A., Morris, R., Figtree, G., Vernon, S. (2020). Electronic Data on STEMI Patients (Stage 1).
2024
- La Gerche, A., Dennis, M., Figtree, G., Kovacic, J., Maris, J., Nehme, Z., Parsons, S., Pflaumer, A., Puranik, R., Stub, D., et al (2024). A Call to Action to Improve Cardiac Arrest Outcomes: A Report From the National Summit for Cardiac Arrest. Heart, Lung, and Circulation. [More Information]
- Kumar, A., Huangfu, G., Figtree, G., Dwivedi, G. (2024). Atherosclerosis as the Damocles' sword of human evolution: insights from nonhuman ape-like primates, ancient human remains, and isolated modern human populations. American Journal of Physiology - Heart and Circulatory Physiology, 326(3), H821-H831. [More Information]
- Nurmohamed, N., Rodriguez, F., Sandhu, A., Nieman, K., Earls, J., Bax, J., Maron, D., Bhatt, D., van Rosendael, A., Danad, I., Figtree, G., et al (2024). Atherosclerosis evaluation and cardiovascular risk estimation using coronary computed tomography angiography. European Heart Journal, 45(20), 1783-1800. [More Information]
- Lan, N., Chih, H., Brennan, A., Dwivedi, G., Figtree, G., Dinh, D., Stub, D., Reid, C., Ihdayhid, A. (2024). Clinical outcomes and coronary artery lesion characteristics of young patients with ST elevation myocardial infarction and no standard modifiable risk factors. Catheterization and Cardiovascular Interventions. [More Information]
- Howden, N., Branch, K., Douglas, P., Gray, M., Budoff, M., Dewey, M., Newby, D., Nicholls, S., Blankstein, R., Fathieh, S., Grieve, S., Figtree, G. (2024). Computed tomographic angiography measures of coronary plaque in clinical trials: opportunities and considerations to accelerate drug translation. Frontiers in Cardovascular Medicine, 11. [More Information]
- Tran, A., Wang, A., Mickaill, J., Strbenac, D., Larance, M., Vernon, S., Grieve, S., Figtree, G., Patrick, E., Yang, J. (2024). Construction and optimization of multi-platform precision pathways for precision medicine. Scientific Reports, 14(Article 4248), 1-11.
- Deshmukh, T., Selvakumar, D., Thavapalachandran, S., Archer, O., Figtree, G., Feneley, M., Grieve, S., Thomas, L., Pathan, F., Chong, J. (2024). Correlation of Noninvasive Cardiac MRI Measures of Left Ventricular Myocardial Function and Invasive PressureVolume Parameters in a Porcine Ischemia-Reperfusion Model. Radiology: Cardiothoracic Imaging, 6(3). [More Information]
- Candelaria, D., Redfern, J., O'Neil, A., Brieger, D., Clark, R., Briffa, T., Bauman, A., Hyun, K., Cunich, M., Figtree, G., Gallagher, R., et al (2024). Data-driven collaborative QUality improvement in Cardiac Rehabilitation (QUICR) to increase program completion: protocol for a cluster randomized controlled trial. BMC Cardiovascular Disorders, 24(1). [More Information]
- Hernandez, A., Amir, O., Bahit, M., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., et al (2024). Effect of Empagliflozin on Heart Failure Outcomes after Acute Myocardial Infarction: Insights from the EMPACT-MI Trial. Circulation, 149(21), 1627-1638. [More Information]
- BUTLER, J., Bahit, M., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., et al (2024). Empagliflozin after Acute Myocardial Infarction. New England Journal of Medicine, 390(16), 1455-1466. [More Information]
- Gray, M., Fatkin, D., Ingles, J., Robertson, E., Figtree, G. (2024). Genetic testing in cardiovascular disease. Medical Journal of Australia, 220(8), 428-434. [More Information]
- Lee, E., Besnier, M., Genetzakis, E., Tang, O., Kott, K., Vernon, S., Gray, M., Grieve, S., Kassiou, M., Figtree, G. (2024). High-Throughput Measure of Mitochondrial Superoxide Levels as a Marker of Coronary Artery Disease to Accelerate Drug Translation in Patient-Derived Endothelial Cells Using Opera Phenix® Technology. International Journal of Molecular Sciences, 25(1). [More Information]
- Desson, Z., Figtree, G., Webster, J., Jennings, G., Redfern, J., Nicholls, S., McNamara, M., Deeming, S., Doyle, K., Ramanathan, S., Morton, R., et al (2024). Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, 38(2), 177-186. [More Information]
- Dakic, A., Wu, J., Wang, T., Huynh, K., Mellett, N., Duong, T., Beyene, H., Yang, J., Figtree, G., Simes, R., et al (2024). Imputation of plasma lipid species to facilitate integration of lipidomic datasets. Nature Communications, 15(1), 1540. [More Information]
- Udell, J., Bauersachs, J., Bayes-Genis, A., Chen, Y., Chopra, V., Figtree, G., Ge, J., Goodman, S., Gotcheva, N., Goto, S., et al (2024). Left Ventricular Function, Congestion, and Effect of Empagliflozin on Heart Failure Risk After Myocardial Infarction. Journal of the American College of Cardiology, 83(23), 2233-2246. [More Information]
- Wu, J., Giles, C., Dakic, A., Beyene, H., Huynh, K., Wang, T., Meikle, T., Olshansky, G., Salim, A., Duong, T., Zhu, D., Yang, J., Grieve, S., Wilson, A., Chow, C., Vernon, S., Gray, M., Figtree, G., et al (2024). Lipidomic Risk Score to Enhance Cardiovascular Risk Stratification for Primary Prevention. Journal of the American College of Cardiology, 84(5), 434-446.
- Lu, J., Bisson, A., Bennamoun, M., Zheng, Y., Sanfilippo, F., Hung, J., Briffa, T., McQuillan, B., Stewart, J., Figtree, G., et al (2024). Predicting multifaceted risks using machine learning in atrial fibrillation: insights from GLORIA-AF study. European Heart Journal - Digital Health, 5(3), 235-246. [More Information]
- Gray, M., Vogel, B., Mehran, R., Leopold, J., Figtree, G. (2024). Primary prevention of cardiovascular disease in women. Climacteric, 27(1), 104-112. [More Information]
- Buckler, A., Kolossváry, M., Konrad, M., Lal, B., Marques, H., Moss, A., Obuchowski, N., van Beek, E., Virmani, R., Williams, M., Figtree, G., et al (2024). Special Report on the Consensus QIBA Profile for Objective Analytical Validation of Non-calcified and High-risk Plaque and Other Biomarkers using Computed Tomography Angiography. Academic Radiology. [More Information]
- Figtree, G., Doyle, K., Nedkoff, L., Cadilhac, D., Kovacic, J. (2024). The national Cardiovascular Health Leadership Research Forum: a new data-driven model placing research at the centre of improving patient outcomes. Medical Journal of Australia. [More Information]
- Kong, G., Mehta, A., Figtree, G., Mamas, M., Ng, G., Chan, K., Chai, P., Low, A., Lee, C., Yeo, T., et al (2024). The prognostic value of metabolic dysfunction-associated steatotic liver disease in acute myocardial infarction: A propensity score-matched analysis. Diabetes, Obesity and Metabolism, 26(8), 3328-3338. [More Information]
- Bate, K., Genetzakis, E., Vescovi, J., Gray, M., Celermajer, D., McGuire, H., Grieve, S., Vernon, S., Cartland, S., Yang, J., Kavurma, M., Figtree, G. (2024). Vascular Cytokines and Atherosclerosis: Differential Serum Levels of TRAIL, IL-18, and OPG in Obstructive Coronary Artery Disease. Biomolecules, 14, 1119. [More Information]
2023
- Karimi Galougahi, K., Zhang, Y., Kienzle, V., Liu, C., Quek, L., Patel, S., Lau, E., Cordina, R., Figtree, G., Celermajer, D. (2023). β3 adrenergic agonism: A novel pathway which improves right ventricular-pulmonary arterial hemodynamics in pulmonary arterial hypertension. Physiological Reports, 11(1). [More Information]
- Kavurma, M., Aitken, S., Boccanfuso, L., Cutmore, C., Passam, F., Patel, S., Hennessy, A., Loa, J., Figtree, G., Golledge, J. (2023). A hidden problem: peripheral artery disease in women. European Heart Journal - Quality of Care and Clinical Outcomes, 9(4), 342-350. [More Information]
- Kong, G., Chin, Y., Lim, J., Ng, C., Kannan, S., Chong, B., Lin, C., Chan, K., Anand, V., Lee, E., Figtree, G., et al (2023). A two-decade population-based study on the effect of hypertension in the general population with obesity in the United States. Obesity, 31(3), 832-840. [More Information]
- Kelly, C., Lan, N., Phan, J., Hng, C., Matthews, A., Rankin, J., Schultz, C., Hillis, G., Reid, C., Dwivedi, G., Figtree, G., et al (2023). Characteristics and Outcomes of Young Patients With ST-Elevation Myocardial Infarction Without Standard Modifiable Risk Factors. American Journal of Cardiology, 202, 81-89. [More Information]
- Figtree, G., Vernon, S., Harmer, J., Gray, M., Arnott, C., Bachour, E., Barsha, G., Brieger, D., Brieger, D., O'Sullivan, J. (2023). Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 82(13), 1343-1359. [More Information]
- Kong, G., Chin, Y., Chong, B., Goh, R., Lim, O., Ng, C., Muthiah, M., Foo, R., Vernon, S., Loh, P., Figtree, G., et al (2023). Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: Results from a global meta-analysis of 1,285,722 patients. International Journal of Cardiology, 371, 432-440. [More Information]
- Deshmukh, T., Kovoor, J., Byth, K., Chow, C., Zaman, S., Chong, J., Figtree, G., Thiagalingam, A., Kovoor, P. (2023). Influence of standard modifiable risk factors on ventricular tachycardia after myocardial infarction. Frontiers in Cardovascular Medicine, 10. [More Information]
- Sokhal, B., Matetic, A., Paul, T., Velagapudi, P., Lambrinou, E., Figtree, G., Rashid, M., Moledina, S., Vassiliou, V., Mallen, C., et al (2023). Management and outcomes of patients admitted with type 2 myocardial infarction with and without standard modifiable risk factors. International Journal of Cardiology, 371, 391-396. [More Information]
- Kott, K., Chan, A., Vernon, S., Hansen, T., Kim, T., De Dreu, M., Gunasegaran, B., Murphy, A., Patrick, E., Psaltis, P., Grieve, S., Yang, J., Fazekas de St Groth, B., McGuire, H., Figtree, G. (2023). Mass cytometry analysis reveals altered immune profiles in patients with coronary artery disease. Clinical & Translational Immunology, 12(11), e1462-1-e1462-18. [More Information]
- Chin, Y., Lim, O., Lin, C., Chan, Y., Kong, G., Ng, C., Chong, B., Syn, N., Chan, K., Muthiah, M., Figtree, G., et al (2023). Meta-Analysis of the Placebo and Nocebo effects associated with Placebo treatment in randomized trials of lipid-lowering therapies. European Heart Journal - Quality of Care and Clinical Outcomes, 9(5), 511-519. [More Information]
- Lee, E., Genetzakis, E., Figtree, G. (2023). Novel Strategies in the Early Detection and Treatment of Endothelial Cell-Specific Mitochondrial Dysfunction in Coronary Artery Disease. Antioxidants, 12(7). [More Information]
- Chan, A., Wu, S., Vernon, S., Tang, O., Figtree, G., Liu, T., Yang, J., Patrick, E. (2023). Overcoming cohort heterogeneity for the prediction of subclinical cardiovascular disease risk. iScience, 26(5), Article 106633 - 1-Article 106633 - 17. [More Information]
- Fathieh, S., Grieve, S., Negishi, K., Figtree, G. (2023). Potential Biological Mediators of Myocardial and Vascular Complications of Air Pollution—A State-of-the-Art Review. Heart, Lung, and Circulation, 32(1), 26-42. [More Information]
- Cho, K., French, J., Figtree, G., Chow, C., Kozor, R. (2023). Rapid access chest pain clinics in Australia and New Zealand. Medical Journal of Australia, 219(4), 168-172. [More Information]
- Kott, K., Genetzakis, E., Gray, M., Hansen, P., McGuire, H., Yang, J., Grieve, S., Vernon, S., Figtree, G. (2023). Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease. Biomolecules, 13(8), 1187-17 pages. [More Information]
- Burgess, S., Shoaib, A., Sharp, A., Ludman, P., Graham, M., Figtree, G., Kontopantelis, E., Rashid, M., Kinnaird, T., Mamas, M. (2023). Sex-Specific Differences in Potent P2Y12Inhibitor Use in British Cardiovascular Intervention Society Registry STEMI Patients. Circulation: Cardiovascular Interventions, 16(9), E012447. [More Information]
- Anand, V., Zhe, E., Chin, Y., Goh, R., Lin, C., Kueh, M., Chong, B., Kong, G., Tay, P., Dalakoti, M., Figtree, G., et al (2023). Socioeconomic deprivation and prognostic outcomes in acute coronary syndrome: A meta-analysis using multidimensional socioeconomic status indices. International Journal of Cardiology, 383, 140-150. [More Information]
- Gallagher, R., Chow, C., Parker, H., Neubeck, L., Celermajer, D., Redfern, J., Tofler, G., Buckley, T., Schumacher, T., Hyun, K., Boroumand, F., Figtree, G. (2023). The effect of a game-based mobile app 'MyHeartMate' to promote lifestyle change in coronary disease patients: a randomized controlled trial. European Heart Journal - Digital Health, 4(1), 33-42. [More Information]
- Chew, N., Ng, C., Tan, D., Kong, G., Lin, C., Chin, Y., Lim, W., Huang, D., Quek, J., Fu, C., Figtree, G., et al (2023). The global burden of metabolic disease: Data from 2000 to 2019. Cell Metabolism, 35(3), 414-428.e3. [More Information]
- Chong, B., Kong, G., Kannan, S., Chew, H., Lin, C., Goh, R., Chin, Y., Tan, D., Chan, K., Lim, W., Figtree, G., et al (2023). The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019. Metabolism: Clinical and Experimental, 141. [More Information]
- Leslie, F., Avis, S., Bagnall, R., Bendall, J., Briffa, T., Brouwer, I., Butters, A., Figtree, G., La Gerche, A., Gray, B., Semsarian, C., Sy, R., Yeates, L., et al (2023). The New South Wales Sudden Cardiac Arrest Registry: A Data Linkage Cohort Study. Heart, Lung, and Circulation, 32(9), 1069-1075. [More Information]
2022
- Nour, D., Allahwala, U., Hansen, P., Figtree, G., Nelson, G., Ward, M., Bhindi, R. (2022). Angiographic predictors of coronary hemodynamics. Future Cardiology, 18(4), 299-308. [More Information]
- Sharma, P., Liu Chung Ming, C., Wang, X., Bienvenu, L., Beck, D., Figtree, G., Boyle, A., Gentile, C. (2022). Biofabrication of advancedin vitro3D models to study ischaemic and doxorubicin-induced myocardial damage. Biofabrication, 14(2), 25003. [More Information]
- Kott, K., Bishop, M., Yang, C., Plasto, T., Cheng, D., Kaplan, A., Cullen, L., Celermajer, D., Meikle, P., Vernon, S., Figtree, G. (2022). Biomarker Development in Cardiology: Reviewing the Past to Inform the Future. Cells, 11(3), 588. [More Information]
- Barraclough, J., Yu, J., Figtree, G., Perkovic, V., Heerspink, H., Neuen, B., Cannon, C., Mahaffey, K., Schutte, A., Neal, B., Arnott, C. (2022). Cardiovascular and renal outcomes with canagliflozin in patients with peripheral arterial disease: Data from the CANVAS Program and CREDENCE trial. Diabetes, Obesity and Metabolism, 24(6), 1072-1083. [More Information]
- Sarraju, A., Bakris, G., Cannon, C., Cherney, D., Damaraju, C., Figtree, G., Gogate, J., Greene, T., Heerspink, H., Januzzi, J., Jardine, M., et al (2022). Cardiovascular Effects of Canagliflozin in Relation to Renal Function and Albuminuria. Journal of the American College of Cardiology, 80(18), 1721-1731. [More Information]
- Mazhar, J., Ekström, K., Kozor, R., Grieve, S., Nepper-Christensen, L., Ahtarovski, K., Kelbæk, H., Høfsten, D., Køber, L., Vejlstrup, N., Vernon, S., Figtree, G., et al (2022). Cardiovascular magnetic resonance characteristics and clinical outcomes of patients with ST-elevation myocardial infarction and no standard modifiable risk factors–A DANAMI-3 substudy. Frontiers in Cardovascular Medicine, 9. [More Information]
- Figtree, G., Redfors, B., Kozor, R., Vernon, S., Grieve, S., Mazhar, J., Thiele, H., Patel, M., Udelson, J., Selker, H., et al (2022). Clinical Outcomes in Patients With ST-Segment Elevation MI and No Standard Modifiable Cardiovascular Risk Factors. JACC: Cardiovascular Interventions, 15(11), 1167-1175. [More Information]
- Sia, C., Ko, J., Zheng, H., Ho, A., Foo, D., Foo, L., Lim, P., Liew, B., Chai, P., Yeo, T., Figtree, G., et al (2022). Comparison of Mortality Outcomes in Acute Myocardial Infarction Patients With or Without Standard Modifiable Cardiovascular Risk Factors. Frontiers in Cardovascular Medicine, 9. [More Information]
- McKinn, S., Batcup, C., Cornell, S., Freeman, N., Doust, J., Bell, K., Figtree, G., Bonner, C. (2022). Decision Support Tools for Coronary Artery Calcium Scoring in the Primary Prevention of Cardiovascular Disease Do Not Meet Health Literacy Needs: A Systematic Environmental Scan and Evaluation. International Journal of Environmental Research and Public Health, 19(18). [More Information]
- Bursill, C., Smith, N., Palpant, N., Tan, I., Sunde, M., Harvey, R., Lewis, B., Figtree, G., Vandenberg, J. (2022). Don't Turn Off the Tap! The Importance of Discovery Science to the Australian Cardiovascular Sector and Improving Clinical Outcomes Into the Future. Heart, Lung, and Circulation, 31(10), 1321-1332. [More Information]
- Li, J., Arnott, C., Heerspink, H., Mbiostat, Q., Cannon, C., Wheeler, D., Charytan, D., Barraclough, J., Figtree, G., Agarwal, R., Neal, B., Jardine, M., et al (2022). Effect of Canagliflozin on Total Cardiovascular Burden in Patients With Diabetes and Chronic Kidney Disease: A Post Hoc Analysis From the CREDENCE Trial. Journal of the American Heart Association, 11(16). [More Information]
- Yu, J., Li, J., Leaver, P., Arnott, C., Huffman, M., Udell, J., Perkovic, V., Mahaffey, K., de Zeeuw, D., Fulcher, G., Neal, B., Figtree, G., et al (2022). Effects of canagliflozin on myocardial infarction: a post hoc analysis of the CANVAS programme and CREDENCE trial. Cardiovascular Research, 118(4), 1103-1114. [More Information]
- Kavurma, M., Bursill, C., Stanley, C., Passam, F., Cartland, S., Patel, S., Loa, J., Figtree, G., Golledge, J., Aitken, S., et al (2022). Endothelial cell dysfunction: Implications for the pathogenesis of peripheral artery disease. Frontiers in Cardovascular Medicine, 9. [More Information]
- Sharma, P., Beck, D., Murtha, L., Figtree, G., Boyle, A., Gentile, C. (2022). Fibulin-3 Deficiency Protects Against Myocardial Injury Following Ischaemia/ Reperfusion in in vitro Cardiac Spheroids. Frontiers in Cardovascular Medicine, 9. [More Information]
- Swaraj, S., Kozor, R., Arnott, C., Di Bartolo, B., Figtree, G. (2022). Heart Failure with Reduced Ejection Fraction—Does Sex Matter? Current Heart Failure Reports, 18(6), 345-352. [More Information]
- Hansen, T., Bubb, K., Schiattarella, G., Ugander, M., Tan, T., Figtree, G. (2022). High-Resolution Transthoracic Echocardiography Accurately Detects Pulmonary Arterial Pressure and Decreased Right Ventricular Contractility in a Mouse Model of Pulmonary Fibrosis and Secondary Pulmonary Hypertension. Journal of the American Heart Association, 11(23). [More Information]
- Figtree, G., Kovacic, J., McGuire, H. (2022). Human susceptibility to coronary artery disease: lessons from chimpanzee resilience. Nature Reviews Cardiology, 19(8), 497-498. [More Information]
- Vernon, S., Kott, K., Hansen, T., Finemore, M., Baumgart, K., Bhindi, R., Yang, J., Hansen, P., Nicholls, S., Celermajer, D., Ward, M., Van Nunen, S., Grieve, S., Figtree, G. (2022). Immunoglobulin E Sensitization to Mammalian Oligosaccharide Galactose-á-1,3 (á-Gal) Is Associated With Noncalcified Plaque, Obstructive Coronary Artery Disease, and ST-Segment-Elevated Myocardial Infarction. Arteriosclerosis, Thrombosis, and Vascular Biology, 42(3), 352-361. [More Information]
- Nolde, J., Hillis, G., Atkins, E., Von Huben, A., Marschner, S., Chan, J., Reid, C., Nelson, M., Figtree, G., Chalmers, J., Usherwood, T., Chow, C., et al (2022). Impact of various night-time period definitions on nocturnal ambulatory blood pressure. Journal of Hypertension, 40(11), 2271-2279. [More Information]
- Mujwara, D., Henno, G., Vernon, S., Peng, S., Di Domenico, P., Schroeder, B., Busby, G., Figtree, G., Bottà, G. (2022). Integrating a Polygenic Risk Score for Coronary Artery Disease as a Risk-Enhancing Factor in the Pooled Cohort Equation: A Cost-Effectiveness Analysis Study. Journal of the American Heart Association, 11(12). [More Information]
- Figtree, G., Vernon, S., Hadziosmanovic, N., Sundström, J., Alfredsson, J., Nicholls, S., Chow, C., Psaltis, P., Rosjo, H., Leosdottir, M., et al (2022). Mortality and Cardiovascular Outcomes in Patients Presenting With Non–ST Elevation Myocardial Infarction Despite No Standard Modifiable Risk Factors: Results From the SWEDEHEART Registry. Journal of the American Heart Association, 11(15). [More Information]
- Moledina, S., Kobo, O., Lakhani, H., Abhishek, A., Parwani, P., Santos Volgman, A., Bond, R., Rashid, M., Figtree, G., Mamas, M. (2022). Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis. IJC Heart & Vasculature, 43. [More Information]
- Figtree, G., Adamson, P., Antoniades, C., Blumenthal, R., Blaha, M., Budoff, M., Celermajer, D., Chan, M., Chow, C., Dey, D., Giannotti, N., Grieve, S., Patel, S., Vernon, S., et al (2022). Noninvasive Plaque Imaging to Accelerate Coronary Artery Disease Drug Development. Circulation, 146(22), 1712-1727. [More Information]
- Kozor, R., Mooney, J., Lowe, H., Kritharides, L., Altman, M., Klimis, H., Thakkar, J., Wynne, D., Thiagalingam, A., Figtree, G., Chow, C. (2022). Rapid Access Chest Pain Clinics: An Australian Cost-Benefit Study. Heart, Lung, and Circulation, 31(2), 177-182. [More Information]
- Ekmejian, A., Bhindi, R., Figtree, G. (2022). Sublingual Nitrates for Patients as a Default in the Post-ACS Discharge Pack: Is It Time for a Rethink? Circulation, 145(11), 791-792. [More Information]
- Figtree, G., Vernon, S., Nicholls, S. (2022). Taking the next steps to implement polygenic risk scoring for improved risk stratification and primary prevention of coronary artery disease. European Journal of Preventive Cardiology, 29(4), 580-587. [More Information]
- Coorey, G., Figtree, G., Fletcher, D., Snelson, V., Vernon, S., Winlaw, D., Grieve, S., McEwan, A., Yang, J., Qian, P., Orchard, J., Kim, J., Patel, S., Redfern, J., et al (2022). The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field. npj Digital Medicine, 5(1), 1-12. [More Information]
- Chin, Y., Ng, C., Chew, N., Kong, G., Lim, W., Tan, D., Chan, K., Tang, A., Huang, D., Chan, M., Figtree, G., et al (2022). The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis. EClinicalMedicine, 54. [More Information]
- Saleh, S., George, J., Kott, K., Meikle, P., Figtree, G. (2022). The Translation and Commercialisation of Biomarkers for Cardiovascular Disease—A Review. Frontiers in Cardovascular Medicine, 9. [More Information]
- May, L., Bartolo, B., Harrison, D., Guzik, T., Drummond, G., Figtree, G., Ritchie, R., Rye, K., De Haan, J. (2022). Translating atherosclerosis research from bench to bedside: navigating the barriers for effective preclinical drug discovery. Clinical Science, 136(23), 1731-1758. [More Information]
2021
- Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A Call to Action for New Global Approaches to Cardiovascular Disease Drug Solutions. Circulation, 144(2), 159-169. [More Information]
- Figtree, G., Broadfoot, K., Casadei, B., Califf, R., Crea, F., Drummond, G., Freedman, J., Guzik, T., Harrison, D., Hausenloy, D., et al (2021). A call to action for new global approaches to cardiovascular disease drug solutions. European Heart Journal, 42(15), 1464-1475. [More Information]
- Kim, T., Tang, O., Vernon, S., Kott, K., Koay, Y., Park, J., James, D., Grieve, S., Speed, T., Yang, P., Figtree, G., John, O., Yang, J. (2021). A hierarchical approach to removal of unwanted variation for large-scale metabolomics data. Nature Communications, 12(1), 4992-1-4992-10. [More Information]
- Paige, E., Doyle, K., Jorm, L., Banks, E., Hsu, M., Nedkoff, L., Briffa, T., Cadilhac, D., Mahoney, R., Verjans, J., Figtree, G., et al (2021). A Versatile Big Data Health System for Australia: Driving Improvements in Cardiovascular Health. Heart, Lung, and Circulation, 30(10), 1467-1476. [More Information]
- Kott, K., Morel-Kopp, M., Vernon, S., Takagi, Y., Di Bartolo, B., Peter, K., Yang, J., Grieve, S., Ward, C., Figtree, G. (2021). Association of global coagulation profiles with cardiovascular risk factors and atherosclerosis: A sex disaggregated analysis from the bioheart-ct study. Journal of the American Heart Association, 10(20), e020604. [More Information]
- Alsaigh, T., Di Bartolo, B., Mulangala, J., Figtree, G., Leeper, N. (2021). Bench-to-Bedside in Vascular Medicine: Optimizing the Translational Pipeline for Patients With Peripheral Artery Disease. Circulation Research, 128(12), 1927-1943. [More Information]
- Bubb, K., Ravindran, D., Cartland, S., Finemore, M., Clayton, Z., Tsang, M., Tang, O., Kavurma, M., Patel, S., Figtree, G. (2021). beta (3) Adrenergic Receptor Stimulation Promotes Reperfusion in Ischemic Limbs in a Murine Diabetic Model. Frontiers in Pharmacology, 12, 666334. [More Information]
- Ciofani, J., Ozorio, G., Don, G., Bernard, E., Figtree, G., Nelson, G. (2021). Cardiac Sarcoidosis Presenting as Cardiogenic Shock and Ventricular Tachycardia. Heart, Lung, and Circulation, 30(10), e112-e114. [More Information]
- Yu, J., Arnott, C., Neuen, B., Heersprink, H., Mahaffey, K., Cannon, C., Khan, S., Baldridge, A., Shah, S., Huang, Y., Figtree, G., Neal, B., et al (2021). Cardiovascular and renal outcomes with canagliflozin according to baseline diuretic use: a post hoc analysis from the CANVAS Program. ESC Heart Failure, 8(2), 1482-1493. [More Information]
- Geraghty, L., Figtree, G., Schutte, A., Patel, S., Woodward, M., Arnott, C. (2021). Cardiovascular Disease in Women: From Pathophysiology to Novel and Emerging Risk Factors. Heart, Lung, and Circulation, 30(1), 9-17. [More Information]
- Tam, C., Gullick, J., Saavedra, A., Vernon, S., Figtree, G., Chow, C., Cretikos, M., Morris, R., William, M., Morris, J., et al (2021). Combining structured and unstructured data in EMRs to create clinically-defined EMR-derived cohorts. BMC Medical Informatics and Decision Making, 21(1), 91. [More Information]
- Sharma, P., Wang, X., Ming, C., Vettori, L., Figtree, G., Boyle, A., Gentile, C. (2021). Considerations for the Bioengineering of Advanced Cardiac In Vitro Models of Myocardial Infarction. Small, 17(15), 2003765. [More Information]
- Vernon, S., Kott, K., Hansen, T., Zhang, K., Cole, B., Coffey, S., Grieve, S., Figtree, G. (2021). Coronary artery disease burden in women poorly explained by traditional risk factors: Sex disaggregated analyses from the BioHEART-CT study. Atherosclerosis, 333, 100-107. [More Information]
- Avis, S., Vernon, S., Hagström, E., Figtree, G. (2021). Coronary artery disease in the absence of traditional risk factors: a call for action. European Heart Journal, 42(37), 3822-3824. [More Information]
- Figtree, G., Vernon, S. (2021). Coronary artery disease patients without standard modifiable risk factors (SMuRFs)- a forgotten group calling out for new discoveries. Cardiovascular Research, 117(6), e76-e78. [More Information]
- Playford, D., Hamilton-Craig, C., Dwivedi, G., Figtree, G. (2021). Examining the Potential for Coronary Artery Calcium (CAC) Scoring for Individuals at Low Cardiovascular Risk. Heart, Lung, and Circulation, 30(12), 1819-1828. [More Information]
- Bubb, K., Tang, O., Gentile, C., Moosavi, S., Hansen, T., Liu, C., Di Bartolo, B., Figtree, G. (2021). FXYD1 Is Protective Against Vascular Dysfunction. Hypertension, 77(6), 2104-2116. [More Information]
- Astell-Burt, T., Navakatikyan, M., Walsan, R., Davis, W., Figtree, G., Arnolda, L., Feng, X. (2021). Green space and cardiovascular health in people with type 2 diabetes. Health & Place, 69, 102554. [More Information]
- Agarwal, A., Peters, S., Chandramouli, C., Lam, C., Figtree, G., Arnott, C. (2021). Guideline-Directed Medical Therapy in Females with Heart Failure with Reduced Ejection Fraction. Current Heart Failure Reports, 18(5), 284-289. [More Information]
- Vernon, S., Tang, O., Kim, T., Chan, A., Kott, K., Park, J., Hansen, T., Koay, Y., Grieve, S., O'Sullivan, J., Yang, J., Figtree, G. (2021). Metabolic Signatures in Coronary Artery Disease: Results from the BioHEART-CT Study. Cells, 10(5), 980. [More Information]
- Figtree, G., Vernon, S., Hadziosmanovic, N., Sundström, J., Alfredsson, J., Arnott, C., Delatour, V., Leósdóttir, M., Hagström, E. (2021). Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data. The Lancet, 397(10279), 1085-1094. [More Information]
- Yousefi-Koma, A., Naghashzadeh, F., Figtree, G., Patel, S., Karimi Galougahi, K. (2021). Multi-modality imaging of inflammation and ischemia for assessment of myocardial injury in Covid-19. Journal of Nuclear Cardiology, 28(6), 3100-3103. [More Information]
- Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A., Malle, E., Bartels, E., Christoffersen, C., Grieve, S., Figtree, G., Davies, M., et al (2021). Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia–reperfusion injury in rats. Scientific Reports, 11(1), 12712-1-12712-18. [More Information]
- Besnier, M., Finemore, M., Yu, C., Kott, K., Vernon, S., Seebacher, N., Genetzakis, E., Furman, A., Tang, O., Davis, R., Hansen, T., Bubb, K., Wise, S., Grieve, S., Di Bartolo, B., Figtree, G., et al (2021). Patient endothelial colony-forming cells to model coronary artery disease susceptibility and unravel the role of dysregulated mitochondrial redox signalling. Antioxidants, 10(10), 1547. [More Information]
- Agbaedeng, T., Noubiap, J., Mofo Mato, E., Chew, D., Figtree, G., Said, M., van der Harst, P. (2021). Polygenic risk score and coronary artery disease: A meta-analysis of 979,286 participant data. Atherosclerosis, 333, 48-55. [More Information]
- Bubb, K., Harmer, J., Finemore, M., Aitken, S., Ali, Z., Billot, L., Chow, C., Golledge, J., Mister, R., Gray, M., Grieve, S., Keech, A., Patel, S., Figtree, G., et al (2021). Protocol for the Stimulating β3- Adrenergic Receptors for Peripheral Artery Disease (STAR- PAD) trial: a double- blinded, randomised, placebo- controlled study evaluating the effects of mirabegron on functional performance in patients with peripheral arterial disease. BMJ Open, 11(9), e049858-1-e049858-10. [More Information]
- Arnott, C., Li, J., Cannon, C., de Zeeuw, D., Neuen, B., Heerspink, H., Charytan, D., Agarwal, A., Huffman, M., Figtree, G., Jardine, M., et al (2021). The effects of canagliflozin on heart failure and cardiovascular death by baseline participant characteristics: Analysis of the CREDENCE trial. Diabetes, Obesity and Metabolism, 23(7), 1652-1659. [More Information]
- Coorey, G., Figtree, G., Fletcher, D., Redfern, J. (2021). The health digital twin: advancing precision cardiovascular medicine. Nature Reviews Cardiology, 18(12), 803-804. [More Information]
- Vogel, B., Acevedo, M., Appelman, Y., Bairey Merz, C., Chieffo, A., Figtree, G., Guerrero, M., Kunadian, V., Lam, C., Maas, A., Mihailidou, A., et al (2021). The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030. The Lancet, 397(10292), 2385-2438. [More Information]
- Kurup, R., Galougahi, K., Figtree, G., Misra, A., Patel, S. (2021). The Role of Colchicine in Atherosclerotic Cardiovascular Disease. Heart, Lung, and Circulation, 30(6), 795-806. [More Information]
- Hure, A., Ramanathan, S., Deeming, S., Figtree, G., Jennings, G., Webster, J., Morton, R., Redfern, J., Doyle, K., Nicholls, S., et al (2021). Translation and Impact of Funded Australian Cardiovascular Research: A Review With Perspective. Heart, Lung, and Circulation, 30(10), 1442-1448. [More Information]
- Zannad, F., Cotter, G., Alonso Garcia, A., George, S., Davison, B., Figtree, G., Prasad, K., Rockhold, F., Schilsky, R., Stockbridge, N., et al (2021). What can heart failure trialists learn from oncology trialists? European Heart Journal, 42(24), 2373-2383. [More Information]
- Barraclough, J., Harmer, J., Yu, J., Figtree, G., Arnott, C. (2021). Why Are We Forgetting Patients With Peripheral Arterial Disease? Heart, Lung, and Circulation, 30(7), 939-942. [More Information]
2020
- Lembo, R., Gullick, J., Chow, C., Figtree, G., Kozor, R. (2020). A Study of Patient Satisfaction and Uncertainty in a Rapid Access Chest Pain Clinic. Heart, Lung, and Circulation, 29(8), e210-e216. [More Information]
- Redfern, J., Figtree, G., Chow, C., Jennings, G., Briffa, T., Gallagher, R., Foreman, R. (2020). Cardiac Rehabilitation and Secondary Prevention Roundtable: Australian Implementation and Research Priorities. Heart, Lung, and Circulation, 29(3), 319-323. [More Information]
- Allahwala, U., Weaver, J., Nelson, G., Nour, D., Ray, M., Ciofani, J., Ward, M., Figtree, G., Hansen, P., Bhindi, R. (2020). Effect of Recruitment of Acute Coronary Collaterals on In-Hospital Mortality and on Left Ventricular Function in Patients Presenting With ST Elevation Myocardial Infarction. American Journal of Cardiology, 125(10), 1455-1460. [More Information]
- Tam, C., Brieger, D., Gullick, J., Morris, J., Saavedra, A., Morris, R., Figtree, G., Vernon, S. (2020). Electronic Data on STEMI Patients (Stage 1).
- Moon, J., Augusto, J., Menacho, K., Andiapen, M., Bowles, R., Burton, M., Welch, S., Bhuva, A., Seraphim, A., Pade, C., Figtree, G., et al (2020). Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19. Wellcome Open Research, 5, 179. [More Information]
- Climie, R., Wu, J., Calkin, A., Chapman, N., Inglis, S., Mirabito Colafella, K., Picone, D., Tan, J., Thomas, E., Viola, H., Wise, S., Figtree, G., et al (2020). Lack of Strategic Funding and Long-Term Job Security Threaten to Have Profound Effects on Cardiovascular Researcher Retention in Australia. Heart, Lung, and Circulation, 29, 1588-1595. [More Information]
- Li, J., Woodward, M., Perkovic, V., Figtree, G., Heerspink, H., Mahaffey, K., de Zeeuw, D., Vercruysse, F., Shaw, W., Matthews, D., Neal, B. (2020). Mediators of the Effects of Canagliflozin on Heart Failure in Patients With Type 2 Diabetes. JACC: Heart Failure, 8(1), 57-66. [More Information]
- Bubb, K., Drummond, G., Figtree, G. (2020). New opportunities for targeting redox dysregulation in cardiovascular disease. Cardiovascular Research, 116(3), 532-544. [More Information]
- Thavapalachandran, S., Grieve, S., Hume, R., Le, T., Raguram, K., Hudson, J., Pouliopoulos, J., Figtree, G., Dye, R., Barry, A., Coffey, S., Rashid, F., Kizana, E., Asli, N., Chong, J., et al (2020). Platelet-derived growth factor-AB improves scar mechanics and vascularity after myocardial infarction. Science Translational Medicine, 12(524), 1-11. [More Information]
- Mazhar, J., Figtree, G., Vernon, S., Karimi Galougahi, K., Carlo, J., Nissen, S., Nicholls, S. (2020). Progression of coronary atherosclerosis in patients without standard modifiable risk factors. American Journal of Preventive Cardiology, 4. [More Information]
- Kott, K., Vernon, S., Hansen, T., De Dreu, M., Das, S., Powell, J., Fazekas de St Groth, B., Di Bartolo, B., McGuire, H., Figtree, G. (2020). Single-Cell Immune Profiling in Coronary Artery Disease: The Role of State-of-the-Art Immunophenotyping With Mass Cytometry in the Diagnosis of Atherosclerosis. Journal of the American Heart Association, 9(24), e017759. [More Information]
- Ritchie, R., Karimigalougahi, K., Figtree, G. (2020). Targeting longevity genes in the battle against diabetic heart disease – is there a gene delivery fountain of youth? European Journal of Heart Failure, 22(9), 1582-1585. [More Information]
- Arnott, C., Neuen, B., Heerspink, H., Figtree, G., Kosiborod, M., Lam, C., Cannon, C., Rosenthal, N., Shaw, W., Mahaffey, K., Neal, B., et al (2020). The effects of combination canagliflozin and glucagon-like peptide-1 receptor agonist therapy on intermediate markers of cardiovascular risk in the CANVAS program. International Journal of Cardiology, 318, 126-129. [More Information]
- Hansen, T., Galougahi, K., Besnier, M., Genetzakis, E., Tsang, M., Finemore, M., O'Brien-Brown, J., Di Bartolo, B., Kassiou, M., Bubb, K., Figtree, G. (2020). The Novel P2X7 Receptor PKT100 Improves Right Ventricular Function and Survival in Pulmonary Hypertension. American Journal of Physiology - Heart and Circulatory Physiology, 319(1), H183-H191. [More Information]
- Bell, J., Figtree, G., Drummond, G. (2020). Using machine learning to ace cardiovascular risk tests. Cardiovascular Research, 116(14), 2173-2174. [More Information]
2019
- Vijapurapu, R., Kozor, R., Hughes, D., Woolfson, P., Jovanovic, A., Deegan, P., Rusk, R., Figtree, G., Tchan, M., Whalley, D., et al (2019). A randomised controlled trial evaluating arrhythmia burden, risk of sudden cardiac death and stroke in patients with Fabry disease: the role of implantable loop recorders (RaILRoAD) compared with current standard practice. Trials, 20(1), 1-10. [More Information]
- Callaghan, F., Bannon, P., Barin, E., Celermajer, D., Jeremy, R., Figtree, G., Grieve, S. (2019). Age-related changes of shape and flow dynamics in healthy adult aortas: A 4D flow MRI study. Journal of Magnetic Resonance Imaging, 49(1), 90-100. [More Information]
- Kott, K., Vernon, S., Hansen, T., Yu, C., Bubb, K., Coffey, S., Sullivan, D., Yang, J., O'Sullivan, J., Chow, C., Patel, S., Chong, J., Celermajer, D., Kritharides, L., Grieve, S., Figtree, G. (2019). Biobanking for discovery of novel cardiovascular biomarkers using imaging-quantified disease burden: protocol for the longitudinal, prospective, BioHEART-CT cohort study. BMJ Open, 9(9), 1-9. [More Information]
- Climie, R., Kingwell, B., Figtree, G. (2019). Building an Academic-Industry Partnership to Tackle Australia's Biggest Health Burden. Heart, Lung, and Circulation, 28(8), 1144-1147. [More Information]
- Zbinden, R., Wollmann, C., Brachmann, J., Michaelsen, J., Steinwender, C., Kovoor, P., Kelle, S., McGavigan, A., Ching, C., Figtree, G., et al (2019). Clinical safety of the ProMRI implantable cardioverter-defibrillator systems during head and lower lumbar magnetic resonance imaging at 3 T: Results of the ProMRI 3T ENHANCED Master study. Europace, 21(11), 1678-1685. [More Information]
- Gallagher, R., Chow, C., Parker, H., Neubeck, L., Celermajer, D., Redfern, J., Tofler, G., Buckley, T., Schumacher, T., Ferry, C., Whitley, A., Figtree, G., et al (2019). Design and rationale of the MyHeartMate study: a randomised controlled trial of a game-based app to promote behaviour change in patients with cardiovascular disease. BMJ Open, 9(5), 1-7. [More Information]
- Figtree, G., Radholm, K., Barrett, T., Perkovic, V., Mahaffey, K., de Zeeuw, D., Fulcher, G., Matthews, D., Shaw, W., Neal, B. (2019). Effects of Canagliflozin on Heart Failure Outcomes Associated with Preserved and Reduced Ejection Fraction in Type 2 Diabetes: Results from the CANVAS Program. Circulation, 139(22), 2591-2593. [More Information]
- Vernon, S., O'Sullivan, J., Figtree, G. (2019). Metabolic signatures of redox-dependent cardiovascular diseases. In Sajal Chakraborti, Naranjan S Dhalla, Nirmal K Ganguly, Madhu Dikshit (Eds.), Oxidative Stress in Heart Diseases., (pp. 159-171). Singapore: Springer Nature Singapore. [More Information]
- Li, M., Wang, A., Quek, L., Vernon, S., Figtree, G., Yang, J., O'Sullivan, J. (2019). Metabolites downstream of predicted loss-of-function variants inform relationship to disease. Molecular Genetics and Metabolism, 128(4), 476-482. [More Information]
- Bubb, K., Ritchie, R., Figtree, G. (2019). Modified redox signalling in vasculature after chronic infusion of the insulin receptor antagonist, S961. Microcirculation, 26(2), 1-10. [More Information]
- Figtree, G., Radholm, K., Neal, B. (2019). Response by Figtree et al to Letter Regarding Article, Canagliflozin and Heart Failure in Type 2 Diabetes Mellitus: Results From the CANVAS Program (Canagliflozin Cardiovascular Assessment Study)"". Circulation, 139(3), 418-419. [More Information]
- Rowell, A., Stedman, W., Janin, P., Diel, N., Ward, M., Kay, S., Delaney, A., Figtree, G. (2019). Silent left ventricular apical ballooning and Takotsubo cardiomyopathy in an Australian intensive care unit. ESC Heart Failure, 6(6), 1262-1265. [More Information]
- Vernon, S., Coffey, S., D’Souza, M., Chow, C., Kilian, J., Hyun, K., Shaw, J., Adams, M., Roberts-Thomson, P., Brieger, D., Figtree, G. (2019). ST-Segment-Elevation Myocardial Infarction (STEMI) Patients Without Standard Modifiable Cardiovascular Risk Factors-How Common Are They, and What Are Their Outcomes? Journal of the American Heart Association, 8(21), 1-11. [More Information]
- Campbell, M., Chabria, M., Figtree, G., Polonchuk, L., Gentile, C. (2019). Stem Cell-Derived Cardiac Spheroids as 3D In Vitro Models of the Human Heart Microenvironment. Methods in Molecular Biology, 2002, 51-59. [More Information]
- Arnott, C., Parsonage, W., Figtree, G. (2019). Tackling Disparities in Heart Care and Disease Outcomes in Women: Insights and Highlights From the Women and Heart Disease Forum. Heart, Lung, and Circulation, 28(10), 1449-1451. [More Information]
- Figtree, G., Bubb, K., Ngo, D. (2019). Testosterone to estradiol ratio and plaque inflammation- mechanistic insights and biomarker potential? Cardiovascular Research, 115(2), 255-257. [More Information]
- Figtree, G., Jennings, G., Nicholls, S., Graham, R. (2019). The Australian Cardiovascular Alliance-Towards an Integrated Whole-of-Nation Strategy to Address Our Major Health Burden. Heart, Lung, and Circulation, 28(2), 198-203. [More Information]
- Vernon, S., Hansen, T., Kott, K., Yang, J., O'Sullivan, J., Figtree, G. (2019). Utilizing state-of-the-art "omics" technology and bioinformatics to identify new biological mechanisms and biomarkers for coronary artery disease. Microcirculation, 26(2), 1-9. [More Information]
2018
- Lawley, C., Broadhouse, K., Callaghan, F., Winlaw, D., Figtree, G., Grieve, S. (2018). 4D flow magnetic resonance imaging: role in pediatric congenital heart disease. Asian Cardiovascular and Thoracic Annals, 26(1), 28-37. [More Information]
- Bonnitcha, P., Grieve, S., Figtree, G. (2018). Clinical imaging of hypoxia: Current status and future directions. Free Radical Biology and Medicine, 126, 296-312. [More Information]
- MacIsaac, A., Figtree, G. (2018). Why are women with ST-elevation myocardial infarction treated differently to men? Medical Journal of Australia, 209(3), 115-116. [More Information]
2017
- Figtree, G., Liu, C., Fry, N., Galougahi, K. (2017). Biomarkers of Oxidative Stress. Patent No. 9,638,699.
- Polonchuk, L., Chabria, M., Badi, L., Hofack, J., Figtree, G., Davies, M., Gentile, C. (2017). Cardiac spheroids as promising in vitro models to study the human heart microenvironment. Scientific Reports, 7(1), 1-12. [More Information]
- Mawad, D., Figtree, G., Gentile, C. (2017). Current Technologies Based on the Knowledge of the Stem Cells Microenvironments. Advances in Experimental Medicine and Biology, 1041, 245-262. [More Information]
- Figtree, G., Nelson, G., Bhindi, R. (2017). Festschrift for Professor Stephen Hunyor — Celebrating his Clinical and Scientific Contribution and the Legacy he has Left at Royal North Shore Hospital, and the Broader Cardiovascular Research Community. Heart, Lung, and Circulation, 26(1), 6-9. [More Information]
- O'Neill, E., Kaur, A., Bishop, D., Shishmarev, D., Kuchel, P., Grieve, S., Figtree, G., Renfrew, A., Bonnitcha, P., New, E. (2017). Hypoxia-responsive cobalt complexes in tumor spheroids: Laser ablation inductively coupled plasma mass spectrometry and magnetic resonance imaging studies. Inorganic Chemistry, 56(16), 9860-9868. [More Information]
- Vernon, S., Coffey, S., Bhindi, R., Hoo, S., Nelson, G., Ward, M., Hansen, P., Asrress, K., Chow, C., Celermajer, D., O'Sullivan, J., Figtree, G. (2017). Increasing proportion of ST elevation myocardial infarction patients with coronary atherosclerosis poorly explained by standard modifiable risk factors. European Journal of Preventive Cardiology, 24(17), 1824-1830. [More Information]
- Kozor, R., Nordin, S., Treibel, T., Rosmini, S., Castelletti, S., Fontana, M., Captur, G., Baig, S., Steeds, R., Hughes, D., Grieve, S., Figtree, G., et al (2017). Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping. European Heart Journal - Cardiovascular Imaging, 18, 1034-1040. [More Information]
- Tate, M., Deo, M., Cao, A., Hood, S., Huynh, K., Kiriazis, H., Du, X., Julius, T., Figtree, G., Dusting, G., et al (2017). Insulin replacement limits progression of diabetic cardiomyopathy in the low-dose streptozotocin-induced diabetic rat. Diabetes and Vascular Disease Research, 14(5), 423-433. [More Information]
- Lawley, C., Lain, S., Figtree, G., Sholler, G., Winlaw, D., Roberts, C. (2017). Mortality, rehospitalizations and costs in children undergoing a cardiac procedure in their first year of life in New South Wales, Australia. International Journal of Cardiology, 241, 156-162. [More Information]
- Callaghan, F., Arnott, C., Figtree, G., Kutty, S., Celermajer, D., Grieve, S. (2017). Quantifying right atrial filling and emptying: A 4D-flow MRI study. Journal of Magnetic Resonance Imaging, 45(4), 1046-1054. [More Information]
- Callaghan, F., Arnott, C., Figtree, G., Kutty, S., Celermajer, D., Grieve, S. (2017). Quantifying right atrial filling and emptying: A 4D-flow MRI study. Journal of Magnetic Resonance Imaging, 45(4), 1-1. [More Information]
- Klimis, H., Thiagalingam, A., Altman, M., Atkins, E., Figtree, G., Lowe, H., Cheung, N., Kovoor, P., Denniss, A., Chow, C. (2017). Rapid-access cardiology services: can these reduce the burden of acute chest pain on Australian and New Zealand health services? Internal Medicine Journal, 47(9), 986-991. [More Information]
- Bubb, K., Birgisdottir, A., Tang, O., Hansen, T., Figtree, G. (2017). Redox modification of caveolar proteins in the cardiovascular system- role in cellular signalling and disease. Free Radical Biology and Medicine, 109, 61-74. [More Information]
- Bubb, K., Kok, C., Tang, O., Rasko, N., Birgisdottir, A., Hansen, T., Ritchie, R., Bhindi, R., Reisman, S., Meyer, C., Karimigalougahi, K., Figtree, G., et al (2017). The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling. Free Radical Biology and Medicine, 108, 585-594. [More Information]
- Figtree, G., Bubb, K., Tang, O., Kizana, E., Gentile, C. (2017). Vascularized Cardiac Spheroids as Novel 3D in vitro Models to Study Cardiac Fibrosis. Cells Tissues Organs, 204(3-Apr), 191-198. [More Information]
- Jiang, L., Gentile, C., Lauto, A., Cui, C., Song, Y., Romeo, T., Silva, S., Tang, O., Sharma, P., Figtree, G., et al (2017). Versatile Fabrication Approach of Conductive Hydrogels via Copolymerization with Vinyl Monomers. ACS Applied Materials and Interfaces, 9(50), 44124-44133. [More Information]
2016
- Ngo, D., Roberts, C., Figtree, G. (2016). Association between interpregnancy interval and future risk of maternal cardiovascular disease-a population-based record linkage study. BJOG, 123(8), 1311-1318. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Gentile, C., Fry, N., Hamilton, E., Hawkins, C., Figtree, G. (2016). Beta3 adrenergic stimulation restores nitric oxide/redox balance and enhances endothelial function in hyperglycemia. Journal of the American Heart Association, 5(2), 1-17. [More Information]
- Kozor, R., Grieve, S., Tchan, M., Callaghan, F., Hamilton-Craig, C., Denaro, C., Moon, J., Figtree, G. (2016). Cardiac involvement in genotype-positive Fabry disease patients assessed by cardiovascular MR. Heart, 102(4), 298-302. [More Information]
- Kozor, R., Grieve, S., Figtree, G., Bhindi, R. (2016). Cardiovascular magnetic resonance, mitral regurgitation and outcomes: the importance of accurate assessment in an era of increasing intervention. Journal of Thoracic Disease, 8(9), E1053-E1056. [More Information]
- Shao, L., Ma, A., Figtree, G., Zhang, P. (2016). Combination Therapy With Coenzyme Q10 and Trimetazidine in Patients With Acute Viral Myocarditis. Journal of Cardiovascular Pharmacology, 68(2), 150-154. [More Information]
- Lyon, A., Bossone, E., Schneider, B., Sechtem, U., Citro, R., Underwood, S., Sheppard, M., Figtree, G., Parodi, G., Akashi, Y., et al (2016). Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 18(1), 8-27. [More Information]
- Evin, M., Broadhouse, K., Callaghan, F., McGrath, R., Glastras, S., Kozor, R., Hocking, S., Lamy, J., Redheuil, A., Kachenoura, N., Fulcher, G., Figtree, G., Grieve, S. (2016). Impact of obesity and epicardial fat on early left atrial dysfunction assessed by cardiac MRI strain analysis. Cardiovascular Diabetology, 15(1), 1-10. [More Information]
- Ngo, A., Roberts, C., Chen, J., Figtree, G. (2016). Interaction of maternal smoking and preterm birth on future risk of maternal cardiovascular disease: A population-based record linkage study. European Journal of Preventive Cardiology, 23(6), 613-620. [More Information]
- Sverdlov, A., Figtree, G., Horowitz, J., Ngo, D. (2016). Interplay between Oxidative Stress and Inflammation in Cardiometabolic Syndrome. Mediators of Inflammation, 2016, 1-3. [More Information]
- Gaikwad, N., Butler, T., Maxwell, R., Shaw, E., Strugnell, W., Chan, J., Figtree, G., Slaughter, R., Hamilton-Craig, C. (2016). Late gadolinium enhancement does occur in Tako-tsubo cardiomyopathy - A quantitative cardiac magnetic resonance and speckle tracking strain study. IJC Heart & Vasculature, 12, 68-74. [More Information]
- Neubeck, A., Gallagher, R., Ingram, K., Celermajer, D., Schumacher, T., Ferry, K., Buckley, T., Redfern, J., Chow, C., Tofler, G., Figtree, G. (2016). MyHeartMate: Development of a Digital Game to Improve Secondary Prevention of Cardiovascular Disease. Abstracts for the 64th Cardiac Society of Australia and New Zealand Annual Scientific Meeting and the International Society for Heart Research Australasian Section Annual Scientific Meeting, Adelaide: Elsevier.
- Hansen, T., Galougahi, K., Celermajer, D., Rasko, N., Tang, O., Bubb, K., Figtree, G. (2016). Oxidative and Nitrosative Signalling in Pulmonary Arterial Hypertension- Implications for Development of Novel Therapies. Pharmacology & Therapeutics, 165, 50-62. [More Information]
- Oh, B., Figtree, G., Costa, D., Eade, T., Hruby, G., Lim, S., Elfiky, A., Martine, N., Rosenthal, D., Clarke, S., Back, M. (2016). Oxidative stress in prostate cancer patients: A systematic review of case control studies. Prostate International, 4(3), 71-87. [More Information]
- Seneviratne, M., Grieve, S., Figtree, G., Garsia, R., Celermajer, D., Adelstein, S., Puranik, R. (2016). Prevalence, distribution and clinical correlates of myocardial fibrosis in systemic lupus erythematosus: a cardiac magnetic resonance study. Lupus, 25(6), 573-581. [More Information]
- Huang, A., Murphy, J., Shaw, E., Kozor, R., Yan, W., Loxton, A., Soo Hoo, S., Figtree, G., Rasmussen, H., Hansen, P., Nelson, G., Bhindi, R., Ward, M. (2016). Routine aspiration thrombectomy improves the diagnosis and management of embolic myocardial infarction. Catheterization and Cardiovascular Interventions, 87(4), 642-647. [More Information]
- Madan, A., Yan, W., Byrne, P., Ward, M., Hansen, P., Whalley, D., Kanagaratnam, L., Figtree, G. (2016). Significance of left atrial appendage filling defects on cardiac CT prior to pulmonary vein isolation for atrial fibrillation. International Journal of Cardiology, 203, 520-522. [More Information]
- Dona, A., Coffey, S., Figtree, G. (2016). Translational and emerging clinical applications of metabolomics in cardiovascular disease diagnosis and treatment. European Journal of Preventive Cardiology, 23(15), 1578-1589. [More Information]
- Callaghan, F., Kozor, R., Sherrah, A., Vallely, M., Celermajer, D., Figtree, G., Grieve, S. (2016). Use of multi-velocity encoding 4D flow MRI to improve quantification of flow patterns in the aorta. Journal of Magnetic Resonance Imaging, 43(2), 352-363. [More Information]
2015
- Kozor, R., Callaghan, F., Nelson, G., Figtree, G., Grieve, S. (2015). 4D Multi-VENC Cardiac MRI: Characterisation of a Functional Stenosis of the Ascending Aorta. Heart, Lung, and Circulation, 24(11), 1134-1135. [More Information]
- Kozor, R., Callaghan, F., Tchan, M., Hamilton-Craig, C., Figtree, G., Grieve, S. (2015). A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease. Journal of Cardiovascular Magnetic Resonance, 17(1), 1-7. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Fry, N., Hamilton, E., Figtree, G., Rasmussen, H. (2015). Beta3-Adrenoceptor activation relieves oxidative inhibition of the cardiac Na+-K+ pump in hyperglycemia induced by insulin receptor blockade. American Journal of Physiology: Cell Physiology, 309(5), C286-C295. [More Information]
- Allahwala, U., Cockburn, J., Shaw, E., Figtree, G., Hansen, P., Bhindi, R. (2015). Clinical utility of optical coherence tomography (OCT) in the optimisation of Absorb bioresorbable vascular scaffold deployment during percutaneous coronary intervention. EuroIntervention, 10(10), 1154-1159. [More Information]
- Mazhar, J., Shaw, E., Allahwala, U., Figtree, G., Bhindi, R. (2015). Comparison of two dimensional quantitative coronary angiography (2D-QCA) with optical coherence tomography (OCT) in the assessment of coronary artery lesion dimensions. IJC Heart & Vasculature, 7, 14-17. [More Information]
- Liang, S., Figtree, G., Aiqun, M., Ping, Z. (2015). GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. Toxicology Letters, 234(3), 162-171. [More Information]
- Liang, S., Aiqun, M., Figtree, G., Ping, Z. (2015). GAPDH-silence preserves H9C2 cells from acute hypoxia and reoxygenation injury. International Journal of Biological Macromolecules, 81, 375-386. [More Information]
- Cockburn, J., Karimi, K., Hoo, S., Rasmussen, H., Hansen, P., Nelson, G., Ward, M., Bhindi, R., Figtree, G. (2015). Outcomes by Day and Night for Patients Bypassing the Emergency Department Presenting with ST-Segment Elevation Myocardial Infarction Identified with a Pre-Hospital Electrocardiogram. Journal of Interventional Cardiology, 28(1), 24-31. [More Information]
- Karimigalougahi, K., Antoniades, C., Nicholls, S., Channon, K., Figtree, G. (2015). Redox biomarkers in cardiovascular medicine. European Heart Journal, 36(25), 1576-1582. [More Information]
- Gnjidic, D., Naganathan, V., Freedman, S., Beer, C., McLachlan, A., Hilmer, S., Figtree, G. (2015). Statin therapy and cognition in older people: What is the evidence? Current Clinical Pharmacology, 10(3), 185-193. [More Information]
- Chia, K., Liu, C., Hamilton, E., Garcia, A., Fry, N., Hannam, W., Figtree, G., Rasmussen, H. (2015). Stimulation of the cardiac myocyte NA+-K+ pump due to reversal of its constitutive oxidative inhibition. American Journal of Physiology: Cell Physiology, 309(4), C239-C250. [More Information]
- Shaw, E., Allahwala, U., Cockburn, J., Hansen, T., Mazhar, J., Figtree, G., Hansen, P., Bhindi, R. (2015). The effect of coronary artery plaque composition, morphology and burden on Absorb bioresorbable vascular scaffold expansion and eccentricity - A detailed analysis with optical coherence tomography. International Journal of Cardiology, 184(1), 230-236. [More Information]
- Grover, S., Bell, G., Lincoff, A., Jeorg, L., Madsen, P., Huang, S., Leow, S., Figtree, G., Chakrabarty, A., Woodman, R., et al (2015). Utility of CMR Markers of Myocardial Injury in Predicting LV Functional Recovery: Results from PROTECTION AMI CMR sub-study. Heart, Lung, and Circulation, 24(9), 891-897. [More Information]
2014
- Grieve, S., Mazhar, J., Callaghan, F., Kok, C., Tandy, S., Bhindi, R., Figtree, G. (2014). Automated Quantification of Myocardial Salvage in a Rat Model of Ischemia-Reperfusion Injury Using 3D High-Resolution Magnetic Resonance Imaging (MRI). Journal of the American Heart Association, 3(4), 1-11. [More Information]
- Murphy, J., Hansen, P., Bhindi, R., Figtree, G., Nelson, G., Ward, M. (2014). Cost Benefit for Assessment of Intermediate Coronary Stenosis with Fractional Flow Reserve in Public and Private Sectors in Australia. Heart, Lung, and Circulation, 23(9), 807-810. [More Information]
- Kozor, R., Pollock, C., Gill, A., Bhindi, R., Figtree, G. (2014). Fabry disease deposition mimicking a cardiac tumour and precipitating heart block. European Heart Journal - Cardiovascular Imaging, 15(8), 869-869. [More Information]
- Karimigalougahi, K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N., Davies, M., Hawkins, C., Rasmussen, H., Figtree, G. (2014). Glutathionylation Mediates Angiotension II-Induced eNOS Uncoupling, Amplifying NADPH Oxidase-Dependent Endothelial Dysfunction. Journal of the American Heart Association, 3(2), 1-11. [More Information]
- Lawley, C., Algert, C., Ford, J., Nippita, T., Figtree, G., Roberts, C. (2014). Heart Valve Prostheses in Pregnancy: Outcomes for Women and Their Infants. Journal of the American Heart Association, 3(3), 1-8. [More Information]
- Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2014). Prosthetic heart valves in pregnancy: a systematic review and meta-analysis protocol. Systematic Reviews, 3, 1-7. [More Information]
- Kozor, R., Grieve, S., Buchholz, S., Kaye, S., Darke, S., Bhindi, R., Figtree, G. (2014). Regular Cocaine Use Is Associated with Increased Systolic Blood Pressure, Aortic Stiffness and Left Ventricular Mass in Young Otherwise Healthy Individuals. PloS One, 9(4), 1-8. [More Information]
2013
- Ho, E., Karimigalougahi, K., Liu, C., Bhindi, R., Figtree, G. (2013). Biological markers of oxidative stress: Applications to cardiovascular research and practice. Redox Biology, 1(1), 483-491. [More Information]
- Grieve, S., Lonborg, J., Mazhar, J., Tan, T., Ho, E., Liu, C., Lay, W., Gill, A., Kuchel, P., Bhindi, R., Figtree, G. (2013). Cardiac magnetic resonance imaging of rapid VCAM-1 up-regulation in myocardial ischemia-reperfusion injury. European Biophysics Journal, 42(1), 61-70. [More Information]
- McMahon, R., Siow, W., Bhindi, R., Hoo, S., Figtree, G., Hansen, P., Nelson, G., Rasmussen, H., Ward, M. (2013). Left bundle branch block without concordant ST changes is rarely associated with acute coronary occlusion. International Journal of Cardiology, 167(4), 1339-1342. [More Information]
- Figtree, G., Bagnall, R., Abdulla, I., Buchholz, S., Karimigalougahi, K., Yan, W., Tan, T., Neil, C., Horowitz, J., Semsarian, C., Ward, M. (2013). No association of G-protein-coupled receptor kinase 5 or β-adrenergic receptor polymorphisms with Takotsubo cardiomyopathy in a large Australian cohort. European Journal of Heart Failure, 15(7), 730-733. [More Information]
- Mazhar, J., Murphy, J., Figtree, G., Hansen, P., Nelson, G., Bhindi, R. (2013). Optical coherence tomography (OCT) as an adjunct to percutaneous coronary intervention; a single centre experience. International Journal of Cardiology, 163(3), e49-e52. [More Information]
- Kanagaratnam, L., Lee, A., Whalley, D., Figtree, G. (2013). Overcoming Artifacts and Fears: Electrophysiology Study and Radiofrequency Ablation in a Parkinsonian Patient with Supraventricular Tachycardia and a Brain Neurostimulator. Pacing And Clinical Electrophysiology, 36(1), 1-3. [More Information]
- Liu, C., Karimigalougahi, K., Weisbrod, R., Hansen, T., Ravaie, R., Nunez, A., Liu, Y., Fry, N., Garcia, A., Hamilton, E., Figtree, G., et al (2013). Oxidative inhibition of the vascular Na+-K+ pump via NADPH oxidase-dependent β1-subunit glutathionylation: Implications for angiotensin II-induced vascular dysfunction. Free Radical Biology and Medicine, 65(2013), 563-572. [More Information]
- Figtree, G., Rasmussen, H., Liu, C. (2013). Oxidative regulation of the na+-k+ pump in cardiac physiology and pathology: clarifying the published evidence. Circulation Research, 112(1), e1-e1. [More Information]
- Karimigalougahi, K., Liu, C., Garcia, A., Fry, N., Hamilton, E., Rasmussen, H., Figtree, G. (2013). Protein kinase-dependent oxidative regulation of the cardiac Na+-K+ pump: evidence from in vivo and in vitro modulation of cell signalling. Journal of Physiology, 591(12), 2999-3015. [More Information]
- Liu, C., Fry, N., Hamilton, E., Chia, K., Garcia, A., Karimigalougahi, K., Figtree, G., Clarke, R., Bundgaard, H., Rasmussen, H. (2013). Redox-dependent regulation of the Na+ -K+ pump: New twists to an old target for treatment of heart failure. Journal of Molecular and Cellular Cardiology, 61, 94-101. [More Information]
- Rayner, B., Figtree, G., Sabaretnam, T., Shang, P., Mazhar, J., Weaver, J., Lay, W., Witting, P., Hunyor, S., Grieve, S., Bhindi, R., et al (2013). Selective Inhibition of the Master Regulator Transcription Factor Egr-1 With Catalytic Oligonucleotides Reduces Myocardial Injury and Improves Left Ventricular Systolic Function in a Preclinical Model of Myocardial Infarction. Journal of the American Heart Association, 2(4), 1-9. [More Information]
- Puckeridge, M., Chapman, B., Conigrave, A., Grieve, S., Figtree, G., Kuchel, P. (2013). Stoichiometric relationship between Na+ ions transported and glucose consumed in human erythrocytes: Bayesian analysis of 23Na and 13C NMR time course data. Biophysical Journal, 104(8), 1676-1684. [More Information]
- Figtree, G., Bhindi, R., Cockburn, J., Wilkes, N., Ward, M., Hansen, P. (2013). Use of optical coherence tomography to guide treatment of an undeployed stent trapped in the right coronary artery to cover a proximal stent outflow dissection. International Journal of Cardiology, 167, e163-e166. [More Information]
- Lonborg, J., Ward, M., Gill, A., Grieve, S., Figtree, G. (2013). Utility of cardiac magnetic resonance in assessing right-sided heart failure in sarcoidosis. BMC Medical Imaging, 13(1), 1-5. [More Information]
- Mazhar, J., Lawley, C., Gill, A., Grieve, S., Figtree, G. (2013). Visualizing pericardial inflammation as the cause of acute chest pain in a patient with a congenital pericardial cyst: the incremental diagnostic value of cardiac magnetic resonance. European Heart Journal, 34(19), 1413-1413. [More Information]
- Lawley, C., Mazhar, J., Grieve, S., Figtree, G. (2013). Visualizing pericardial inflammation in Dressler's syndrome with cardiac magnetic resonance imaging. International Journal of Cardiology, 168(1), e32-e33. [More Information]
2012
- Lay, W., Rayner, B., Sabaretnam, T., Figtree, G., Jackson, C., Hunyor, S., Bhindi, R. (2012). Activated protein C improves left ventricular remodelling after ischemia-reperfusion injury in rats. International Journal of Cardiology, 159(3), 246-248. [More Information]
- Huang, A., Mathur, M., Figtree, G. (2012). Cardiac magnetic resonance characterization of an iatrogenic left ventricular apical pseudo- aneurysm. European journal of Echocardiography, 13(12), 1000-1000. [More Information]
- Buchholz, S., Shakil, A., Figtree, G., Hansen, P., Bhindi, R. (2012). Diagnosis and management of patent foramen ovale. Postgraduate Medical Journal, 88(1038), 217-225. [More Information]
- Kozor, R., Nelson, G., Figtree, G. (2012). Extensive mid-wall myocardial oedema after aborted sudden death in hypertrophic cardiomyopathy. International Journal of Cardiology, 154(1), e14-e15. [More Information]
- Ward, M., Figtree, G. (2012). Letter by Ward and Figtree article, "mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease". Circulation, 126(6), e82-e82. [More Information]
- Yan, W., Nelson, G., Figtree, G., Bhindi, R. (2012). Overcoming Limited Depth Penetration of Optical Coherence Tomography With Wire Bias. J A C C: Cardiovascular Interventions, 5(1), e1-e2. [More Information]
- Figtree, G., Karimigalougahi, K., Liu, C., Rasmussen, H. (2012). Oxidative regulation of the Na+ -K+ pump in the cardiovascular system. Free Radical Biology and Medicine, 53(12), 2263-2268. [More Information]
- Murphy, J., Kozor, R., Figtree, G., Ward, M., Bhindi, R. (2012). Percutaneous coronary intervention via the radial artery: comparison of procedural success in emergency versus non-emergency cases. Cardiovascular Revascularization Medicine, 13(5), 277-280. [More Information]
- Murphy, J., Kozor, R., Figtree, G., Hansen, P., Rasmussen, H., Ward, M., Nelson, G., Bhindi, R. (2012). Procedural and in-patient outcomes in patients aged 80 years or older undergoing contemporary primary percutaneous coronary intervention. EuroIntervention, 8(8), 912-919. [More Information]
- Rowell, A., Figtree, M., Dimmick, S., Kotsiou, G., Grieve, S., Figtree, G. (2012). Recurrent right ventricular echinococcosis characterized by cardiac magnetic resonance. International Journal of Cardiology, 158(2), 293-294. [More Information]
- Fong, L., Mathur, M., Bhindi, R., Figtree, G. (2012). Right atrial Merkel cell tumour metastasis characterization using a multimodality approach. European Heart Journal, 33(17), 2205-2205. [More Information]
- Liu, C., Garcia, A., Mahmmoud, Y., Hamilton, E., Galougahi, K., Fry, N., Figtree, G., Cornelius, F., Clarke, R., Rasmussen, H. (2012). Susceptibility of β1 Na+ -K+ pump subunit to glutathionylation and oxidative inhibition depends on conformational state of pump. Journal of Biological Chemistry, 287(15), 12353-12364. [More Information]
2011
- Figtree, G., Lonborg, J., Grieve, S., Ward, M., Bhindi, R. (2011). Cardiac Magnetic Resonance Imaging for the Interventional Cardiologist. J A C C: Cardiovascular Interventions, 4(2), 137-148. [More Information]
- Hamilton, E., Figtree, G., Rasmussen, H. (2011). Consideration of natriuretic peptide receptor C. Circulation Research, 108(4), e4-e5. [More Information]
- Bibert, S., Liu, C., Figtree, G., Garcia, A., Hamilton, E., Marassi, F., Sweadner, K., Cornelius, F., Geering, K., Rasmussen, H. (2011). FXYD Proteins Reverse Inhibition of the Na+-K+ Pump Mediated by Glutathionylation of Its beta 1 Subunit. Journal of Biological Chemistry, 286(21), 18562-18572. [More Information]
- Ho, E., Bhindi, R., Ashley, E., Figtree, G. (2011). Genetic analysis in cardiovascular disease: a clinical perspective. Cardiology in Review, 19(2), 81-89. [More Information]
- Karimigalougahi, K., Harden, M., Maher, R., Gill, A., Bhindi, R., Grieve, S., Brady, P., Figtree, G. (2011). Incremental Diagnostic Value of Magnetic Resonance Imaging in the Characterization of a Cardiac Mass. Journal of the American College of Cardiology, 58(10), e19-e19. [More Information]
- Bhindi, R., Grieve, S., Figtree, G. (2011). Micromyocardial infarction in apical hypertrophic cardiomyopathy with obliterative coronary artery bridging. International Journal of Cardiology, 151(1), e24-e25. [More Information]
- Yu, C., Grieve, S., Brazier, D., Bhindi, R., Figtree, G. (2011). Post-infarct ventricular thrombus: a critical diagnosis made by cardiac magnetic resonance imaging. Heart, Lung, and Circulation, 20(6), 373-373. [More Information]
- Montfort, J., Maher, R., Grieve, S., Figtree, G. (2011). Syringomyelia: A rare extracardiac contributor to syncope detected incidentally by CMR. International Journal of Cardiology, 150(2), e62-e64. [More Information]
- Yu, C., Brazier, D., Bhindi, R., Figtree, G., Ward, M. (2011). Use of computer tomography coronary angiography in assessment of aorto-ostial coronary disease. International Journal of Cardiology, 147(1), 153-154. [More Information]
2010
- White, C., Liu, C., Garcia, A., Hamilton, E., Chia, K., Figtree, G., Rasmussen, H. (2010). Activation of cAMP-dependent signaling induces oxidative modification of the cardiac Na+-K+ pump and inhibits its activity. Journal of Biological Chemistry, 285(18), 13712-13720. [More Information]
- Robaei, D., Grieve, S., Nelson, G., Figtree, G. (2010). Cocaine-induced epicardial coronary artery thrombosis resulting in extensive myocardial injury assessed by cardiac magnetic resonance imaging. European Heart Journal, 31(20), 2446. [More Information]
- Buchholz, S., Grieve, S., Maher, R., Figtree, G. (2010). Cocaine-induced myocardial injury seen as multiple mid-wall foci of late enhancement by contrast-enhanced cardiac magnetic resonance imaging. European Heart Journal, 31(11), 1422. [More Information]
- Lonborg, J., Mathur, M., Grieve, S., Bhindi, R., Ward, M., Lowe, H., McCrohon, J., Figtree, G. (2010). Constrictive Pericarditis Diagnosed by Cardiac Magnetic Resonance. Journal of the American College of Cardiology, 56(20), e39-e39. [More Information]
- Testa, L., Biondi Zoccai, G., Valgimigli, M., Latini, R., Pizzocri, S., Lanotte, S., Laudisa, M., Brambilla, N., Ward, M., Figtree, G., et al (2010). Current concepts on antiplatelet therapy: focus on the novel thienopyridine and non-thienopyridine agents. Advances in Hematology, 2010, 595934. [More Information]
- Figtree, G., Guzik, T., Robinson, B., Channon, K., Watkins, H. (2010). Functional estrogen receptor alpha promoter polymorphism is associated with improved endothelial-dependent vasolidation. International Journal of Cardiology, 143(2), 207-208. [More Information]
- Grieve, S., Bhindi, R., Seow, J., Doyle, A., Turner, A., Tomka, J., Lay, W., Gill, A., Hunyor, S., Figtree, G. (2010). Microvascular obstruction by intracoronary delivery of mesenchymal stem cells and quantification of resulting myocardial infarction by cardiac magnetic resonance. Circulation. Heart Failure, 3(3), e5-e6. [More Information]
- Rasmussen, H., Liu, C., Figtree, G. (2010). Reversible oxidative modification: implications for cardiovascular physiology and pathophysiology. Trends In Cardiovascular Medicine, 20(3), 85-90. [More Information]
- Figtree, G., Thiruvallapan, N., Brereton, J., Whalley, D., Tofler, G. (2010). The effect of elevated right atrial pressure due to pulmonary emboli on detection of patent foramen ovale and potential paradoxical embolus. Journal of Cardiovascular Medicine (Hagerstown), 11(1), 61-63. [More Information]
- Bundgaard, H., Liu, C., Garcia, A., Hamilton, E., Huang, Y., Chia, K., Hunyor, S., Figtree, G., Rasmussen, H. (2010). {beta}3 Adrenergic Stimulation of the Cardiac Na+-K+ Pump by Reversal of an Inhibitory Oxidative Modification. Circulation, 122, 2699-2708. [More Information]
2009
- White, C., Figtree, G., Liu, C., Garcia, A., Hamilton, E., Chia, K., Rasmussen, H. (2009). Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH oxidase. American Journal of Physiology: Cell Physiology, 296(4), C693-C700. [More Information]
- Figtree, G., Noonan, J., Bhindi, R., Collins, P. (2009). Estrogen Receptor Polymorphisms: Significance to Human Physiology, Disease and Therapy. Recent Patents on DNA and Gene Sequences, , 0. [More Information]
- Figtree, G. (2009). Genetic Variants in Estrogen Signaling Pathways. Germany: VDM Verlag.
- Bhindi, R., Figtree, G. (2009). Percutaneous coronary intervention versus coronary-artery bypass grafting. New England Journal of Medicine, 360(25), 2672; author reply 2674-5. [More Information]
- Figtree, G., Robinson, B., Channon, K., Watkins, H. (2009). Polymorphism upstream of estrogen receptor alpha reverses negative regulation of transcription. International Journal of Cardiology, 144(1), 86-8. [More Information]
- Figtree, G., Liu, C., Bibert, S., Hamilton, E., Garcia, A., White, C., Chia, K., Cornelius, F., Geering, K., Rasmussen, H. (2009). Reversible oxidative modification: A key mechanism of Na+-K + pump regulation. Circulation Research, 105(2), 185-193. [More Information]
- Rasmussen, H., Figtree, G., Krum, H., Bundgaard, H. (2009). The use of beta3-adrenergic receptor agonists in the treatment of heart failure. Current Opinion in Investigational Drugs (Print), 10(9), 955-962. [More Information]
2008
- Figtree, G., Grieve, S., Speller, B., Geiger, M., Robinson, B., Channon, K., Ragoussis, J., Collins, P., Watkins, H. (2008). A commonly occurring polymorphism upstream of the estrogen receptor alpha alters transcription and is associated with increased HDL. Atherosclerosis, 199(2), 354-361. [More Information]
- William, M., Hamilton, E., Bundgaard, H., Garcia, A., Chia, K., Figtree, G., Rasmussen, H. (2008). Natriuretic peptides stimulate the cardiac sodium pump via NPR-C coupled NOS activation. American Journal of Physiology: Cell Physiology, 294(4), C1067-C1073. [More Information]
- White, C., Hamilton, E., Garcia, A., Wang, D., Chia, K., Figtree, G., Rasmussen, H. (2008). Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes. American Journal of Physiology: Cell Physiology, 294, C572-C578. [More Information]
2007
- Rasmussen, H., Figtree, G. (2007). "Don't flog the heart!" - development of specific drug therapies for heart failure. Critical Care and Resuscitation, 9(4), 364-369. [More Information]
2006
- Goodstadt, L., Powell, T., Figtree, G. (2006). 17β-Estradiol Potentiates the Cardiac Cystic Fibrosis Transmembrane Conductance Regulator Chloride Current in Guinea-pig Ventricular Myocytes. The Journal of Physiological Sciences, 56(1), 29-37. [More Information]
- Figtree, G., Kindmark, A., Lind, L., Grundberg, E., Speller, B., Robinson, B., Channon, K., Watkins, H. (2006). Novel estrogen receptor alpha promoter polymorphism increases ventricular hypertrophic response to hypertension. Journal of Steroid Biochemistry and Molecular Biology, 103(2), 110-118. [More Information]
- Figtree, G., Watkins, H., Robinson, B., Channon, K. (2006). Novel polymorphism in estrogen receptor alpha reverses negative transcriptional regulation and is associated with improved endothelial-dependent vasodilation. American Heart Association Annual Scientific Sessions 2005, United States: American Heart Association.
2004
- Figtree, G., Robinson, B. (2004). Estrogen Receptor Polymorphisms In Common Disease:Recent Developments. Current Opinion in Endocrinology, Diabetes and Obesity, 11(3), 141-146. [More Information]
2003
- Figtree, G., McDonald, D., Watkins, H., Channon, K. (2003). Truncated Estrogen Receptor α 46-kDa Isoform in Human Endothelial Cells: Relationship to Acute Activation of Nitric Oxide Synthase. Circulation, 107(1), 120-126. [More Information]
- Cooper, L., Clifton-Bligh, P., Nery, M., Figtree, G., Twigg, S., Hibbert, E., Robinson, B. (2003). Vitamin D supplementation and bone mineral density in early postmenopausal women. American Journal of Clinical Nutrition, 77(5), 1324-1329.
Selected Grants
2024
- Using CHIP as a cost-effective tool for early detection of cardiovascular disease, Tang O, Figtree G, Heart Research Australia/Donation
- POPSTEM: Patient-specific cardiac stem cell villages for personalised therapeutic design, Powell J, Figtree G, Department of Health and Aged Care (Federal - administered by NHMRC)/2023 MRFF Stem Cell Therapies Mission
- Commercialising the results of heart research with the aim of reducing the incidence of heart attacks and carrying out the detailed business plan of the Recipient., Figtree G, DVC Research/CRFI-Irma Margaret Rosalie Downie - Bequest (Heart Research)
2023
- Dissecting the susceptibility of humans to coronary artery disease (CAD), Tang O, McGuire H, Figtree G, Patrick E, Gray M, Heart Research Australia/Research Grant
- Improving early diagnosis and treatment of CAD- above and beyond standard modifiable risk factors (SMuRFs), Figtree G, Xiang M, Yang J, Grieve S, Cordwell S, McGuire H, Vernon S, Office of Global Engagement/Ignition Grants
- Rewarding Research 2024, Figtree G, Faculty of Medicine and Health/FMH Rewarding Research Success
- CVD research program funding support, Figtree G, Faculty of Medicine and Health/Internal Research
- Clinical and health economics implications of routine CTCA for emergency department assessment of Aboriginal and Torres Strait Islander people at risk of acute coronary syndrome, Cullen L, Figtree G, Parsonage W, Stephensen L, Mahoney R, Greenslade J, Department of Health and Aged Care (Federal - administered by NHMRC)/Cardiovascular Health Mission - 2022 Cardiovascular Health Grant
2022
- Dissecting the susceptibility of humans to coronary artery disease (CAD), Ng H, McGuire H, Figtree G, Patrick E, Gray M, Heart Research Australia/Research Grant
- CTCA-POC: CT Coronary Angiography Inspired Point-of-Care Technology for Enhanced Diagnosis and Monitoring of Coronary Artery Disease, Ju A, Li Z, Figtree G, Grieve S, Department of Health and Aged Care (Federal - administered by NHMRC)/2021 MRFF Cardiovascular Health Mission
- Endothelial Cells: an Underappreciated Therapeutic Target in HFpEF, Figtree G, National Heart Foundation of Australia/Vanguard Grant
- Targeting the mitochondrial oxidative phenotype in coronary artery disease (CAD) patient-derived cells using high-throughput drug screening approach, Ng H, Figtree G, Lee E, National Heart Foundation of Australia/NSW CVRN VCCRI Innovation Grant
- Novel anti-inflammatory treatment to protect against maladaptive cardiac remodelingand repair after myocardial infarction., Barsha G, Genetzakis E, Figtree G, Kassiou M, Gilchrist J, Tang O, Heart Research Australia/Research Grant
- Innovative solutions towards reducing heart attacks- beyond classical risk factors, Figtree G, National Health and Medical Research Council (NHMRC)/Investigator Grant
- Strategies for prevention of coronary artery disease in people without traditional risk factors, Vernon S, Figtree G, National Heart Foundation of Australia/Postdoctoral Fellowships (Biomedical, Clinical, Public Health, Health Services)
- Epredia CryoStar NX70 Cryostat 220-240V, 50Hz, Figtree G, Aubrey K, Saad S, National Health and Medical Research Council (NHMRC)/Equipment Grant
- Small molecule inhibitors of the P2X7 receptor as a safe and effective way of tackling the inflammatory contribution to atherosclerosis TTRA, Figtree G, Kassiou M, MTP Connect/Research Grant
- Targeting the unmet needs in coronary artery disease- from bedside to bench to bedside, Figtree G, NSW Health/Cardiovascular Disease Senior Scientist Grants
- Towards Remote Patient Monitoring of Heart Failure Using Event-driven AI Systems, Dwivedi G, Bennamoun M, Eshraghian J, Boussaid F, Kavehei O, Ihdayhid A, Hillis G, Patel S, Figtree G, Department of Health and Aged Care (Federal - administered by NHMRC)/MRFF - 2021 Cardiovascular Health Grant Opportunity
- Improving differentiation between and myocardial to improve patient outcomes, Figtree G, Dind A, Heart Research Australia/Research Support
- Identifying and addressing barriers and enablers to implementing best-practice cardiac rehabilitation: the Quality Improvement in Cardiac Rehabilitation (QUICR) Cluster-Randomised Controlled Trial, Gallagher R, Redfern J, Brieger D, Bauman A, Hyun K, Cunich M, Figtree G, Department of Health and Aged Care (Federal)/MRFF - Cardiovascular Health Mission
- Sydney Health Partners Cardiovascular Clinical Academic Group, Chow C, Figtree G, Sydney Health Partners (Sydney Local Health District)/SHP Stream Funding
- Use of blood Extracellular Vesicles as biomarkers for hidden coronary artery disease in patients, Figtree G, Besnier M, Heart Research Australia/Research Grant
- Australian Stroke and Heart Research Accelerator (ASHRA), Chow C, Kritharides L, Ugander M, Chiang J, Laranjo L, Thiagalingam A, Figtree G, MTP Connect/Research Grant
2021
- A new paradigm to tackle redox-mediated cardiac hypertrophy and fibrosis in heart failure with preserved ejection fraction, Figtree G, Di Bartolo B, Besnier M, Passioura T, National Heart Foundation of Australia/Vanguard Grant
- Ultracentrifuge, Little C, McCracken S, Figtree G, National Health and Medical Research Council (NHMRC)/Equipment Grant
- CRE for Better Outcomes in Inflammatory Arthritis, March L, Thomas R, Lassere M, Buchbinder R, Hill C, Keen H, Wechalekar M, Munro J, Figtree G, Schofield D, National Health and Medical Research Council (NHMRC)/Centres of Research Excellence
- Predictive Modelling: Application of machine learning to the development of a metabolic risk score for cardiovascular disease and a patient/clinician interface to effectively deliver risk information, Miekle P, Figtree G, Chow C, Carrington M, National Heart Foundation of Australia/Strategic Predictive Modelling Grant
- New Frontiers in Personalised Prevention of Coronary Artery Disease, Figtree G, Celemajer D, Chow C, Fazekas de St Groth B, Drummond G, Ellinor P, Grieve S, Jenkins A, Kassiou M, Keech A, Kovacic J, Larance M, Marwick T, McGuire H, Meikle P, Nicholls S, O'Sullivan J, Peter K, Ritchie R, Shaw J, Simes R, Walley T, Wilson A, Department of Health and Aged Care (Federal)/MRFF - Frontier Health and Medical Research Program, Stage One
- Guardian Angel: Implementation of a peer support program for people with heart disease, Briffa T, Redfern J, Gallagher R, Maiorana A, Bauman A, Hackett M, Figtree G, Hyun K, Department of Health and Aged Care (Federal)/MRFF - Cardiovascular Health Mission
- Health4Me: Improving adolescent physical activity and nutrition behaviours via primary care, Hackett M, Partridge S, Mihrshahi S, Redfern J, Steinbeck K, Figtree G, Gallagher R, Hyun K, Kang M, Department of Health and Aged Care (Federal)/MRFF - Primary Health Care Research
- PARTNERSHIP FOR PRECISION PREVENTION IN CAD (PPP-CAD), Figtree G, Kelly P, Wilson A, Redfern J, Usherwood T, Jennings G, Grieve S, National Health and Medical Research Council (NHMRC)/Partnership Projects
2020
- Unravelling the calcification-inflammation axis to predict the risk of heart disease, Figtree G, Di Bartolo B, McGuire H, Heart Research Australia/Research Grant
- NHMRC Centre of Research Excellence for Better Outcomes in Coronary Artery Disease, Figtree G, Grieve S, Nicholls S, Chow C, Brown A, Jenkins A, Peter K, Psaltis P, Yang J, Meikle P, National Health and Medical Research Council (NHMRC)/Centres of Research Excellence
- Shifting the dial in early disease detection and personalised prevention for coronary artery disease, Figtree G, Chow C, Grieve S, Jenkins A, Yang J, NSW Health/Synergy Seeding Grant
2019
- What is the therapeutic efficacy of the novel P2X7R antagonist, SMW139, in attenuating diabetes associated -atherosclerosis and diabetic cardiomyopathy, Di Bartolo B, Kassiou M, Figtree G, National Heart Foundation of Australia/Vanguard Grant
- Ministerial Award for Cardiovascular Research Excellence 2019, Figtree G, National Heart Foundation of Australia/Research Support
- The BioHEART Cohort, Figtree G, NSW Health/Health Statewide Biobank
- Blockade of Orexin Signalling in Hypertension The BOSH Study, Figtree G, Carrive P, Grunstein R, Perkovic V, National Heart Foundation of Australia/Vanguard Grant
- Automated extraction of clinical data and outcomes from EMR to enhance discovery of new markers of coronary artery disease, Figtree G, Tam C, Vernon S, University of Sydney/Sydney Catalyst Pilot - Seed Funding Grant
- Discovering and translating new markers and mechanisms of atherosclerosis, Figtree G, NSW Health/Cardiovascular Disease Clinician Scientist Grants
2018
- Discovering New Mechanisms and Early Markers of Coronary Artery Disease - the BioHEART Study, Figtree G, Heart Research Australia/Research Grant
- Precision Immune Profiling for Improved Coronary Artery Disease Risk Detection, McGuire H, Figtree G, Hansen T, Fazekas de St Groth B, National Heart Foundation of Australia/Vanguard Grant
- Ketone and metabolic profile to understand and optimize the benefit/safety profile of canagliflozin in patients with Type 2 Diabetes and cardiovascular risk, Figtree G, O'Sullivan J, Janssen Research & Development, LLC (USA)/Research Grant
- Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury, Baell J, Figtree G, Ritchie R, National Health and Medical Research Council (NHMRC)/Development Grants
- A clinical trial to assess effectiveness of beta-3 adrenergic receptor agonists in peripheral arterial disease, Bubb K, Figtree G, Patel S, Grieve S, National Heart Foundation of Australia/Vanguard Grant
- Establishment of novel therapies for pulmonary hypertension, Karimigalougahi K, Figtree G, NSW Health/Early Mid Career Fellowship
- Identifying novel mechanisms and markers of coronary artery disease, Figtree G, Heart Research Australia/Research Support
- From fundamental mechanistic discoveries to strategic methods for early detection and treatment of cardiovascular disease, Figtree G, National Health and Medical Research Council (NHMRC)/Practitioner Fellowships
- Beta 3 adrenergic receptor stimulation as a novel treatment for limb and wound complications associated with Type 2 diabetes, Bubb K, Figtree G, Diabetes Australia Research Trust (DART)/Research Grants
2017
- Cardiology Rapid Access Clinics, Chow C, Figtree G, Kritharides L, Celermajer D, Thiagalingam A, Department of Health and Aged Care (Federal)/MRFF - Rapid Applied Research Translation (RART) - Sydney Health Partners
- RART MRFF- G Figtree, Figtree G, Northern Clinical School/Cardiology Rapid Access Clinics
- Vevo 3100 Preclinical Imaging Platform, Howell V, Little C, Figtree G, University of Sydney/Equipment Grant
- Cardiovascular Research Initiative (Pilot), Figtree G, DVC Research/DVCR Strategic Investment
- Gemma Figtree - SRRRP DVCR-722, Figtree G, DVC Research/Strategic Research Recruitment and Retention Program (SRRRP)
- Preparing the foundations for a fully integrated electronic chest pain pathway, Gullick J, Brieger D, Morris J, Chow C, Figtree G, Saavedra A, Shaw T, Miller A, Ritchie A, Guney S, Agency for Clinical Innovation (NSW)/Research Support
- George and Mary Thompson Fellowship, Levick S, Figtree G, Northern Sydney Local Health District (NSLHD)/George and Mary Thompson Fellowship
2016
- Promoting engagement in secondary prevention behaviours after acute coronary syndrome through game strategies: development and evaluation of the MyHeartMate prototype in practice, Gallagher R, Figtree G, Neubeck A, Chow C, Chow C, National Heart Foundation of Australia/Vanguard Grant
- A new paradigm in redox-mediated cardiac fibrosis, Figtree G, Blaxall B, Kizana E, Xie Z, hayward C, Gentile C, National Health and Medical Research Council (NHMRC)/Project Grants
- Evaluation and optimisation of rapid access cardiology models of care, Brieger D, Celermajer D, Chow C, Figtree G, Kritharides L, Leeder S, Lowe H, Thiagalingam A, National Health and Medical Research Council (NHMRC)/Translational Research Projects
2015
- A novel redox biomarker reflecting oxidative inhibition of a key membrane protein to predict heart failure events, Figtree G, Campbell D, Jenkins A, National Heart Foundation of Australia/Vanguard Grant
- Gamifying Secondary Preventative Strategies After Myocardial Infarction, Neubeck A, Figtree G, Charles Perkins Centre/Research Support
- Outcomes following a cardiac procedure in the first six years of life, Lain S, Roberts C, Lawley C, Figtree G, HeartKids Australia/Grants in Aid
- Australia-Harvard Fellowship 2015, Prof Kathleen Sweadner & Dr Elena Arystarkhova, Figtree G, Harvard Club of Australia Foundation/Australia - Harvard Fellowship
2014
- Oxidative regulation of the Na pump- a new player in vascular function in health and disease, Figtree G, Bursill C, Bhindi R, Channon K, Hawkins C, Davies B, Cohen R, National Health and Medical Research Council (NHMRC)/Project Grants
- Novel, prognostic MRI parameters in pulmonary hypertension, Figtree G, Grieve S, Karimi K, Celermajer D, National Heart Foundation of Australia/Vanguard Grant
- Salary Support - Laboratory Manager/Senior Scientist support for Oxidative Signaling Laboratory, Figtree G, Heart Research Australia/Research Support FPRx8437 SCHx24971
- Pregnancy as a stress test determining mothers cardiovascular risk, Figtree G, Roberts C, Morris J, Ford J, National Heart Foundation of Australia/Vanguard Grant
- PA for research and travel, Figtree G, Heart Research Australia/Travel Support FPRx8437 SCHx27165
2013
- Level 1 - Improving risk stratification and targeted treatment of patients with heart attack (project funding for NHMRC CDF APP1062262), Figtree G, National Heart Foundation of Australia/Future Leader Fellowship
- ROS-inhibition of the Na pump and vascular function in vivo, Figtree G, Heart Research Australia/Research Support FPRx8437 SCHx24971
- Clinical CDF Level 2 - Oxidative stress and myocardial infarction, Figtree G, National Health and Medical Research Council (NHMRC)/Career Development Fellowships
2012
- Effect of beta 3 adrenergic receptor signaling on redox-mediated platelet hyperactivity and hypercoagulable state in diabetes, Figtree G, Karimigalougahi K, Heart Research Australia/Research Support
- New approach to protecting the heart from oxidative stress in heart attack, Figtree G, DVC Research/Bridging Support Grant
2011
- FXYDI and effects on ischaemia reperfusion injury, Figtree G, St George Hospital/Research Support
- PHOSPHOLEMMAN: A CARDIAC MEMBRANE PROTEIN WITH CAPACITY TO REDUCE MYOCARDIAL ISCHAEMIA REPERFUSION INJURY, Figtree G, Sylvia and Charles Viertel Charitable Foundation/Viertel Clinical Investigator Awards
2010
- PLM: a rescue protein in heart attack, Figtree G, Heart Research Australia/Research Support
- Diffusion Tensor Imaging in the assessment of myocardial microarchitecture:implications for health and disease, Grieve S, Figtree G, The Royal Australian and New Zealand College of Radiologists/Research Grant
- FXYDI and effects on ischaemia reperfusion injury, Figtree G, DVC Research/Bridging Support Grant
2009
- Molecular mechanism of insulin induced Na-K pump stimulation in cardiac myocytes, Liu C, Rasmussen H, Figtree G, Heart Research Australia/Research Support
- Reversing oxidative inhibition of the Na-K pump by beta3 adrenergic agonists: implications for heart failure therapy, Rasmussen H, Figtree G, McLachlan C, National Health and Medical Research Council (NHMRC)/Project Grants
- Therapeutic Silencing of Egr-1 by Novel Catalytic Oligodeoxynucleotides for The Treatment of Acute Myocardial Infarction, Bhindi R, Figtree G, McCrohon J, Grieve S, National Health and Medical Research Council (NHMRC)/Project Grants
2008
- Effects of irreversible oxidative modification of reactive cysteine on the B1 subunit of the Na-k pump on its regulation in the cardiac myocytes, Figtree G, Royal Australasian College of Physicians/Foundation for High Blood Pressure Research Fellowship
- Rapid and reversible ocidative modification: a key mechanism of hormonal regulation of the cardiac Na-K, Rasmussen H, Figtree G, Liu C, Heart Research Australia/Research Support
- Establishment of a High Field (3T) Cardiac Magnetic Resonance Imaging Research Unit at Royal North Shore Hospital, University of Sydney, Figtree G, Faculty of Medicine and Health/Medical Foundation
2007
- Estrogen receptor alpha: a candidate gene for altered vascular reactivity and Tako-tsubo phenomenon, Figtree G, Ward M, Heart Research Australia/Research Support
2006
- Mechanisms of oxidative regulation of the cardiac sodium pump: possible role of s-glutathionylation, Figtree G, Royal Australasian College of Physicians/Scholarship